A Health Action Process Approach Online Intervention for... | NCT05124522

Studies
A Health Action Process Approach Online Intervention for People With Multiple Sclerosis

NCT05124522

Sponsor

University of Illinois at Urbana-Champaign

Status

Active, not recruiting

Last Update Posted

Aug 24, 2025Actual

Enrollment

60Estimated

Phase

Not Applicable

Conditions

Multiple Sclerosis

Interventions

MSPA eClass

Countries

United States

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

ID	Type	Description	Link
RG-1706-27718	Other Grant/Funding Number	National Multiple Sclerosis Society

Status Module

Record Verification Date

Aug 2025

Overall Recruitment Status or Expanded Access Status

Active, not recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Oct 25, 2021Actual

Primary Completion Date

Apr 30, 2026Estimated

Completion Date

Dec 31, 2026Estimated

First Submitted Date

Oct 25, 2021

First Submission Date that Met QC Criteria

Nov 5, 2021

First Posted Date

Nov 18, 2021Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Aug 18, 2025

Last Update Posted Date

Aug 24, 2025Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Not provided

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

The purpose of this study is to implement the person-centered internet-based Health Action Process Approach to promoting physical activity in people with Multiple Sclerosis (i.e., eHAPA-MS online intervention) and assess the intervention's effectiveness and adherence.

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

60Estimated

Label	Type	Description	Intervention Names
MSPA eClass	Experimental		Behavioral: MSPA eClass
Waiting list	No Intervention

Name	Type	Description	Arm Group Labels	Other Names
MSPA eClass	Behavioral	An 8-week MS-HAPA Internet-based intervention	MSPA eClass

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
The Health Action Process Approach Battery	The battery measures risk perception, exercise benefits, motivation, and volition. "change" is being assessed.	Through study completion, an average of 1 month

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

are 18 years old and above;
any type of multiple sclerosis
have not maintained 30 minutes of MVPA accumulated per day for 2 days of the week during the previous 6 months;
be relapse-free for the past 30 days;
show low risk for contraindications of physical activity indicated by no more than a single 'yes' response on the Physical Activity Readiness Questionnaire;
be able to walk with or without an assistive device;
are willing to be randomized to an intervention or control group, complete the surveys and questionnaires, and wear an accelerometer during the intervention period;
have a reliable Internet access.

Exclusion Criteria:

have a score >14 for the leisure score index of the Godin Leisure-Time Exercise Questionnaire;
No computer or mobile device access with the internet.
Patient determined disease steps (PDDS) Score = 7 i.e., using a wheelchair or scooter most of the time, or PDDS Score = 8 being bedridden.
Anyone living outside of the United States of America.
Anyone who is unable to speak, read and write in English.
not willing to be randomized to an intervention or control group, complete the surveys and questionnaires, and wear an accelerometer during the intervention period.

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

Not provided

Sampling Method

Not provided

Name	Affiliation	Role
Chungyi Chiu, PhD	University of Illinois Urbana-Champaign	Principal Investigator

Facility	Status	City	State	ZIP	Country	Contacts
University of Illinois Urbana-Champaign		Champaign	Illinois	61820	United States

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
40455827	Derived	Chiu C, Sridharan V, Khaliji M, Sajib MRUZ, Gao X, Zackowski K. Patient-Centered, Theory-Based, Online Intervention to Promote a Physically Active Lifestyle for People With Multiple Sclerosis: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2025 Jul 17;14:e66091. doi: 10.2196/66091.

ID	Term
D009103	Multiple Sclerosis
D009043	Motor Activity

ID	Term
D020278	Demyelinating Autoimmune Diseases, CNS
D020274	Autoimmune Diseases of the Nervous System
D009422	Nervous System Diseases
D003711	Demyelinating Diseases