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Coronary heart disease is one of the most serious diseases that endanger people's health. Complex coronary artery disease is critical and has high mortality. Therefore, it is urgent to explore the best treatment method for complex coronary artery disease. Some previous studies have shown that patients with left main coronary artery disease with a SYNTAX score> 32 points, and diabetic/non-diabetic three-vessel disease patients with coronary heart disease with a SYNTAX score > 22 points, CABG is recommended for revascularization. However, with the continuous innovation of surgical technology and the rapid development of surgical instruments, the treatment of patients with complex coronary artery disease is increasing. Therefore, it is necessary to investigate the effects of different revascularization strategies on long-term prognosis in patients with complex coronary artery disease (SYNTAX score > 22 points).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CABG group | CABG group |
| |
| HCR group | HCR group |
| |
| PCI group | PCI group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| The procedures include PCI, CABG and HCR | Procedure | The procedures include PCI, CABG and HCR |
|
| Measure | Description | Time Frame |
|---|---|---|
| MACCE | Major adverse cardiovascular and cerebrovascular events (MACCE) at 1 year, including all-cause death, non-fatal myocardial infarction, ischemia-driven revascularization, and non-fatal stroke | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| All cause death | All-cause death is defined as death from cardiovascular causes, death from non-cardiovascular causes, and death from unknown causes. | 1 year |
| Cardiovascular death | Cardiovascular death |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with complex coronary artery disease
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Miao Yu, Doctor | Contact | 13811879285 | evelynym@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Dongmei Shi | Beijing Anzhen Hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| 1 year |
| Non-fatal myocardial infarction | Non-fatal myocardial infarction | 1 year |
| Ischemia-driven revascularization | Ischemia-driven revascularization | 1 year |
| Non-fatal stroke | Stroke is defined as a neurological deficit with symptoms or signs that last at least 24 hours and imaging studies (CT or MRI) confirm the presence of cerebral infarction or cerebral hemorrhage. | 1 year |
| The composite endpoints including all-cause death, non-fatal myocardial infarction, and ischemia-driven revascularization | The composite endpoints including all-cause death, non-fatal myocardial infarction, and ischemia-driven revascularization | 1 year |
| The composite endpoints including cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke | The composite endpoints including cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke | 1 year |
| The composite endpoints including cardiovascular death or nonfatal myocardial infarction | The composite endpoints including cardiovascular death or nonfatal myocardial infarction | 1 year |
| All bleeding events defined by the BARC bleeding criteria | All bleeding events defined by the BARC bleeding criteria | 1 year |
| Type 2, 3 and 5 bleeding events defined by the BARC bleeding criteria | Type 2, 3 and 5 bleeding events defined by the BARC bleeding criteria | 1 year |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |