Juvenile Essential Arterial Hypertension and Vascular Function

Juvenile Essential Arterial Hypertension and Vascular Reactivity in Systemic and Cerebral Circulation

The main goal of this study is to investigate the association of the juvenile essential arterial hypertension with systemic micro- and macrovascular reactivity and cerebral vascular function, and to examine the potential impact of elevated oxidative stress on this associations.

Inclusion Criteria:

• healthy normotensive children and children with essential arterial hypertension

Exclusion Criteria:

• secondary arterial hypertension
• other systemic diseases with immunopathology
• neurodegenerative diseasesat
• children that use therapy which has a high impact on vascular or immunological function (immunotherapy, immunosuppressive therapy, sistemic corticosteroid therapy etc..).