• mHealth App Intervention to Improve Medication Adherence

  NCT04577157

  CompletedInterventionalNot ApplicableUpdated Mar 17, 2022
• Hypertension Treatment Adherence Improving Trial

  NCT04565548

  Unknown statusInterventionalNot ApplicableUpdated Aug 4, 2021
• Control of Blood Pressure and Risk Attenuation-rural Bangladesh, Pakistan, Sri Lanka, Feasibility Study

  NCT02341651

  CompletedInterventionalNot ApplicableUpdated Feb 6, 2025
• DCP3 Based Multi-component Intervention for Hypertension Management and Control

  NCT04336631

  CompletedInterventionalNot ApplicableUpdated Apr 8, 2020
• Assessing the Feasibility of Multimedia Interventions to Reduce Blood Pressure in Marginalized Hypertensive Communities of Karachi, Pakistan

  NCT07131176

  Not yet recruitingInterventionalNot ApplicableUpdated Aug 20, 2025
• SUPPORT-HEART-PK: Effectiveness, Implementation, and Economic Evaluation of Implementation, and Theory-Based Digital Self-Management Intervention for Heart Failure Management

  NCT07580508

  Not yet recruitingInterventionalNot ApplicableUpdated Jul 10, 2026

ClinicalTrials.gov ID

NCT05106790

Lead Sponsor

Universiti Putra MalaysiaOTHER

Overall Status

Unknown status

Study Type

Interventional

Phase

Not Applicable

Enrollment

1,440Estimated

Last Update Posted

May 17, 2022Actual

Start Date

Jul 1, 2022Estimated

Primary Completion Date

Aug 1, 2023Estimated

Completion Date

Sep 15, 2023Estimated

Official Title

Efficacy of mHealth and Education-led Peer Counseling of Patients With Hypertension and Coronary Artery Disease: a Double-blinded Pragmatic Randomized Control Trial With Factorial Design, Pakistan

Brief Summary

In Pakistan, poor medication adherence is a key operational factor in the prevalence of uncontrolled hypertension. Mobile phone treatments based on technology are at the forefront and are a reasonably low-cost strategy for combating the latest health concerns associated with poor adherence. On the other hand, conservative approaches to counseling are also found effective. This study will look at how a mHealth-based strategy and an educational-led peer counseling intervention can help hypertensive patients with coronary artery disease lower their systolic blood pressure.

Detailed Description

In Pakistan, hypertension is a serious public health concern. Hypertension affects 18.9% of teenagers over the age of 15 and 33% of adults over the age of 45; however, only around 3% of hypertensive individuals have their blood pressure regulated to 140/90 mm Hg or lower. The majority of hypertensive patients are found to have blood pressure that is out of control. The majority of those undergoing therapies were judged to be non-compliant. According to the study, adherence to cardiac medications ranged from 27 to 77 percent, while adherence to stroke medications was around 68 percent. According to a recent study, 37.7% of patients did not take their antihypertensive medication as advised.

Interventions to help hypertensive patients in controlling blood pressure show potential to alter their behavior and lead to better outcomes, but delivering them at a cheap cost is difficult. Although evidence is scarce, several trials examining clinical interventions utilizing conventional health education support while others employing a mobile health strategy, both showed significant results. For a low-resource country, we built cost-effective models that are integrated with clinical care for patients with hypertension. The goal of this trial is to assess the effectiveness of mHealth intervention with clinical educational support and educational support with peer counseling to improve blood pressure control in hypertensive patients when compared to standard care.

• Treatment Adherence and Compliance

• Educational support with peer counseling
• mHealth intervention
• mHealth intervention and Educational support with peer counseling

Ages Eligible for Study

Adult (18-64)Older Adult (65+)

Sexes Eligible for Study

All

Accepts Healthy Volunteers

No

Eligibility Criteria

Inclusion Criteria:

• Participants with age 21 to 70 years
• Participants who have been registered as hypertensive with comorbidity of coronary artery disease in the Outpatient Departments (OPDs) of one of the three public teaching hospitals in Lahore, for at least last one month
• Participants on antihypertensive drugs
• The participants with stable coronary artery disease who are treated in an outpatient setting
• Participants who are willing to sign a written informed consent form, must have a smartphone with the WhatsApp application installed and be able to read Urdu/English.
• Participants with smartphones and have internet access

Exclusion Criteria:

Participants who suffer from some type of malignancy and require adjustment of drugs

• Participants with any biological condition that makes it difficult for them to read write, communicate or hear phone calls
• Participants in hypertensive emergency blood pressure >220/120 mmHg
• Participants with pregnancy(self-reporting)
• Participants in their period of lactation

Primary Purpose

Health Services Research

Allocation

Randomized

Interventional Model

Factorial Assignment

Masking

Double

Lead Sponsor

Universiti Putra MalaysiaOTHER

drarshedchaudhary@gmail.com+923337474464

drarshedchaudhary@gmail.com+923337474464

drarshedchaudhary@gmail.com+923337474464