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Inpatient rehabilitation of severe-to-critical COVID-19 patients(A longitudinal, single-center retrospective cohort)
Patients who underwent intensive care at least two days and classified as severe-to-critical COVID-19 (WHO ordinal scale 5-7) were enrolled. Patients received comprehensive rehabilitation including active exercise program, nutritional support, and psychological support.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Rehabilitative intervention | Other | Active rehabilitation programs were done for all patients. Participants were asked to attend exercise program at PT room or bedside. Exercise program was offered once or twice daily on weekdays, by trained kinesiologists. In PT programs, most patients performed strengthening exercise of lower extremities, balance training, sit-up training, sit-to-stand training and gait training for about 30 minutes. Each program was individualized to participants' current physical function. In bedside programs, patients also underwent strengthening exercise and balance training without gait training for about 10 minutes. The duration of exercise program at PT room depends on the patient's condition(upto 1 month). |
| Measure | Description | Time Frame |
|---|---|---|
| Change of Functional Ambulation Classification | 0~5 score. FAC 0(Nonfunctional ambulator), FAC1(Ambulator, dependent on physical assistance - Indicates a patient who requires continuous manual contact to support body weight as well as to maintain balance or to assist coordination), FAC 2(Ambulator, dependent on physical assistance - Indicates a patient who requires intermittent or continuous light touch to assist balance or coordination), FAC3(Ambulator, dependent on supervision), FAC4(Ambulator, independent level surface only), FAC5(Ambulator, independent). Higher score means better outcome. | at baseline, immediately after rehabilitation completion, and 1-month after rehabilitation completion |
| Measure | Description | Time Frame |
|---|---|---|
| Change of Appendicular skeletal muscle mass index (ASMI) | [Kilogram Per Square Meter] | at baseline, immediately after rehabilitation completion, and 1-month after rehabilitation completion |
| Change of Medical Research Council (MRC) sum score |
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Inclusion Criteria:
COVID-19 patients who
Exclusion Criteria:
COVID-19 patients who died (WHO ordinal scale 8) before discharge were excluded
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Severe COVID-19 (WHO ordinal scale 5-7) who participated in the inpatient rehabilitation program
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| Name | Affiliation | Role |
|---|---|---|
| Jaewon Beom, MD, PhD | Department of Rehabilitation Medicine, Seoul National University Bundang Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Bundang Hospital | Seongnam-si | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36038958 | Derived | Woo H, Lee S, Lee HS, Chae HJ, Jung J, Song MJ, Lim SY, Lee YJ, Cho YJ, Kim ES, Kim HB, Lim JY, Song KH, Beom J. Comprehensive Rehabilitation in Severely Ill Inpatients With COVID-19: A Cohort Study in a Tertiary Hospital. J Korean Med Sci. 2022 Aug 29;37(34):e262. doi: 10.3346/jkms.2022.37.e262. |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D016638 | Critical Illness |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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0~60 score.
| at baseline, immediately after rehabilitation completion, and 1-month after rehabilitation completion |
| Change of handgrip strength | [Lb]. | at baseline, immediately after rehabilitation completion, and 1-month after rehabilitation completion |
| Change of number of 1-min sit-to-stand | Number of repetitions of sit-to-stand within one minute. Higher score means better outcome. | at baseline, immediately after rehabilitation completion, and 1-month after rehabilitation completion |
| Change of walking speed | [meter per second]. Walking speed is measured by 10-meter walking test. If a patient cannot accomplish 10-meter walking test, 4-meter walking test is used instead. Higher score means better outcome. | at baseline, immediately after rehabilitation completion, and 1-month after rehabilitation completion |
| Change of Berg balance scale | 0~56 score. Berg balance scale is 14-item objective measure that assesses static balance and fall risk in adults. Each item consists of a five-point ordinal scale(0 to 4), with 0 indicating the lowest level of function and 4 the highest level of function. Higher score means better outcome. | at baseline, immediately after rehabilitation completion, and 1-month after rehabilitation completion |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |