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To investigate the value of ultrasound elastography in differentiating endometriomas from ovarian hemorrhagic cysts
The participants will be subjected to:
Personal, Obstetric and gynecological History taking.
Clinical examination.
B-mode ultrasonography was performed to characterize the adnexal masses morphologically.
Color Doppler ultrasound.
Grayscale and elastographic ultrasound examination, which will be done using acoustic radiation force impulse (ARFI) imaging with virtual touch quantification (VTQ). Five consecutive measurements were recorded for each lesion from the region identified as the region of interest (ROI) and the median of these measurements was recorded as the shear wave velocity (SWV) value of the lesion. In virtual touch quantification (VTQ) the shear wave speed is expressed in m/s. Only numerical results will be taken into consideration.
. Realtime elastographic and B-mode images simultaneously will appear as a two-panel image. Elastogram appeared in the region of interest (ROI) box to determine the target ovarian lesion and surrounding tissue, then elasticity colour code will be classified in 5 patterns : pattern 1, an absent or a very small hard area; pattern 2, hard area 45 per cent; pattern 4, peripheral hard and central soft areas; pattern 5, hard area occupying entire solid component with or without soft rim. Strain index will be analyzed, which will be obtained by comparing the absolute strain value of solid component of ovarian cyst with that of surrounding soft tissue.
The invistigator will reevaluate the lesions 4 weeks after the initial assessment to see the possible changes in the size and/or configuration of the lesions with B-mode and elastographic ultrasonography.
Lesion will be evaluated as endometriomas and referred for surgery when shows no significant changes in size and configuration.
Hemorrhagic cyst diagnosis will be made if the lesion had resolved on follow-up.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| evaluate the value of ultrasound elastography in dignosis of endometriomas | Active Comparator | evaluation of endometrioma by ultrasound elastography and will be repeated after 4 weeks |
|
| evaluate the value of ultrasound elastography in ovarian hemorrhagic cysts | Active Comparator | revaluation of ovarian hemorrhagic cyst by ultrasound elastography and noticing the change of values |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ultrasound elastography | Device | strain ratio and resistivity index |
|
| Measure | Description | Time Frame |
|---|---|---|
| evalute the value of ultrasound elastography in differentiation in endometriomas and ovarian hemorrhagic cysts | the cut of value of strain ratio in diagnosis of endometrioma and ovarian hemorrhagic cyst | 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| hala hafez, resident | Contact | 00201027292006 | halahafez193@gmail.com | |
| alaa mosbah, professor | Contact | alaamosbah@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Alaa mosbah, professor | Mansoura university faculty of medicine,obestetric and gynecology department | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mansoura University | Recruiting | Al Mansurah | Dakahlia Governorate | 35111 | Egypt |
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| ID | Term |
|---|---|
| D004715 | Endometriosis |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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Parallel Assignment
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Single investigator
| D000091662 | Genital Diseases |