PLAIAR-Trial: Platelets in Inflammation and Resolution

PlaIaR-Trial: Platelets in Inflammation and Resolution.

Detection and determination of platelets in bronchoalveolar lavage fluid and blood in ARDS and non-ARDS-patients. Correlation with phenotype and inflammation parameters in blood and outcome parameters.

Inclusion Criteria:

• Routine bronchoscopy
• Patient in perioperative setting
• Age >=18 years
• Consent

Exclusion Criteria:

• Active or recent (in past 7 days) bleeding in upper airways
• Recent traumatic injury of the lung associated with (micro-)hemorrhage
• Blood aspiration
• Pregnancy
• Age<18 years
• Acute kidney injury / Chronic kidney failure / Dialysis
• Transplantation
• HIV
• Hematologic diseases
• Immunosuppression
• Anti-Platelet-Therapy