For symptomatic gall bladder disorders (cholelithiasis and cholecystitis), laparoscopic cholecystectomy (LC) has been considered as the gold standard treatment. However, these minimally invasive technique is associated with acute moderate pain during the 24 hours postoperative, which is routinely managed using opioids. The transversus abdominis plane (TAP) block has been used as part of a multimodal analgesia strategy. Besides, Wang et al found that TAP block is more effective than a conventional pain control, but not significatively different from another local incisional pain control that is port site infiltration.So, the aim of this study, is to compare the analgesic efficacy and safety of trocar-site infiltration with ropivacaine with ultrasound-guided TAP block following laparoscopic cholecystectomy when used as part of multimodal analgesia.

Inclusion Criteria:

• BMI < 30 kg/m2
• Scheduled for laparoscopic cholecystectomy
• ASA grade I, II and III

Exclusion Criteria:

• Bile duct exploration, insertion of a T-drain or patients with acute cholecystitis
• Conversion to open cholecystectomy or if the surgery exceeded 200 minutes
• Severe systemic disease
• Patients on analgesics for any reason
• History of allergy to local anesthetics
• An ongoing pregnancy
• Patient refusal