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This is a prospective real world registry study, aiming to explore the effectiveness and safety of endovascular treatment of acute ischemic stroke in a Chinese population.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| endovascular treatment | Device | all enrolled patients must receive endovascular treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of patients with modified Rankin Score 0 to 2 | the minimum and maximum values of modified Rankin Score are 0 and 6, respectively; higher score mean a worse outcome | Day 90 |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of patients with modified Rankin Score 0 to 1 | the minimum and maximum values of modified Rankin Score are 0 and 6, respectively; higher score mean a worse outcome | Day 90 |
| Distribution of modified Rankin Score |
| Measure | Description | Time Frame |
|---|---|---|
| neuroimaging associated with clinical outcome | neuroimaging included brain CT, MRI or digital subtraction angiography | 48 hours |
| changes in serum biomarkers | biomarker included Matrix metalloproteinases, proinflammatory cytokines, and etc. |
Inclusion Criteria:
Exclusion Criteria:
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acute ischemic stroke with large vessel oclussion
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hui-Sheng Chen | Shenyang | Liaoning | 110840 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41766997 | Derived | Cui C, Liu L, Chen HS. Association of the neutrophil percentage-to-albumin ratio after endovascular treatment and 3-month clinical outcomes. Front Neurol. 2026 Feb 12;17:1768949. doi: 10.3389/fneur.2026.1768949. eCollection 2026. | |
| 37638196 | Derived | Liu L, Nguyen TN, Chen HS. Endovascular Treatment for Acute Ischemic Stroke in China: a study protocol for a prospective, national, multi-center, registry study. Front Neurol. 2023 Aug 10;14:1171718. doi: 10.3389/fneur.2023.1171718. eCollection 2023. |
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| ID | Term |
|---|---|
| D000083242 | Ischemic Stroke |
| ID | Term |
|---|---|
| D020521 | Stroke |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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the minimum and maximum values of modified Rankin Score are 0 and 6, respectively; higher score mean a worse outcome
| Day 90 |
| Changes in National Institute of Health stroke scale (NIHSS) | the minimum and maximum values of NIHSS are 0 and 24, respectively; higher NIHSS mean a worse outcome | 24 hours, 48 hours, and 2 weeks |
| Proportion of symptomatic intracranial hemorrhage (sICH) | sICH was defined as 4 or more increase in NIHSS caused by hemorrhage | 48 hours |
| Proportion of death | death due to any cause | 7 days |
| 48 hours |
| dynamic changes of TCD data associated | transcranial Doppler (TCD) data including blood velocity and pulse index, which will be collected at some centers | 24 hours |
| dynamic changes of cortical blood oxygen saturation by near infrared spectroscopy | The data will be collected at some centers | 24 hours |
| D009422 |
| Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |