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This is a GWAS study that aims to identify possible candidate genes associate to epilepsy by exploring single nucleotide polymorphism (SNP) in a group of epilepsy, in the Kazakh population. The investigators hypothesize that the careful phenotyping of the subject sand matching with increase the power to find SNP significantly associate with epilepsy
A genome-wide association study (GWAS) is an approach used in genetics research to associate specific genetic variations with particular diseases. The method involves scanning the genomes from many different people and looking for genetic markers that can be used to predict the presence of a disease. Once such genetic markers are identified, they can be used to understand how genes contribute to the disease and develop better prevention and treatment strategies
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental group: | Patients with epilepsy |
| |
| Control group | Patients without epilepsy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DNA analysis | Genetic | GWAS |
|
| Measure | Description | Time Frame |
|---|---|---|
| number of SNPs associated with epilepsy | Using GWAS to identify candidate genes associate with epilepsy | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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Children of Kazakh ethnic group
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| Name | Affiliation | Role |
|---|---|---|
| Altynshash Jaxybayeva | Astana Medical University, Nur-Sultan, Kazakhstan | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Altynshash Jaxybayeva | Almaty | Kazakhstan |
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| ID | Term |
|---|---|
| D004827 | Epilepsy |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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Blood