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Patients undergoing hybrid AF ablation second stage catheter ablation have the posterior left atrium mapped to see it if is electrically isolated. This is done via a standard electrophysiogical study in accordance with routine clinical practice.
Investigators propose to check left atrium posterior wall isolation via oesophageal pacing and compare this to findings from invasive study
Oesophageal temporary pacing of the heart is an established treatment in heart block and several catheters are licenced for this purpose with minimal procedural risks. Due to the position of the oesophagus, pacing from the oesophagus could sense and pace the posterior left atrium. If the posterior wall could be demonstrated to be electrically isolated with oesophageal pacing then invasive electrophysiological study such as the second stage of a hybrid AF ablation would be unnecessary.
This would save patients from undergoing invasive left atrial mapping and exposure to the consequent risks of the procedure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oesophageal Pacing Arm | Experimental | Patients undergoing atrial fibrillation ablation to isolate the left atrial posterior wall via catheter or staged hybrid ablation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oesophageal pacing after left atrial posterior wall isolation | Device | Following AF ablation with the aim of isolating the left atrial posterior wall oesophageal pacing and sensing is performed to check for left atrial posterior wall. entrance and exit block. |
| Measure | Description | Time Frame |
|---|---|---|
| Left atrial posterior wall isolation | Measured via invasive left atrial mapping | Through study completion, an average of 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| Complication rate | Documentation of the number of complications caused by the oesophageal pacing procedure | Through study completion, an average of 4 years |
| Feasibility of using device | The success rate of left atrial posterior wall isolation. |
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Inclusion Criteria: • subjects capable of giving informed consent,
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Guy Haywood, MD | University Hospital Plymouth NHS Trust | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Derriford Hospital | Plymouth | United Kingdom |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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| Through study completion, an average of 4 years |
| D013568 |
| Pathological Conditions, Signs and Symptoms |