1-to identify the prognostic value of serum bicarbonate and serum electrolytes at time of admission and their association with development of complications ,length of hospital stay ,prognosis and mortality in hospitalized cirrhotic patient

the purpose of this study will be explore the impact of data obtained for the arterial blood gas parameters and serum bicarbonate and electrolytes at the time of hospital admission on adverse clinical outcomes ,duration of length of hospital stay and mortality in patients with cirrhosis .Furthermore incorporation these parameters into model of end stage liver disease could help to improve the prognostic value of MELDscore in comparison to the prognostic value of traditional equation of original MELD and child score

Inclusion Criteria:

patients with confirmed diagnosis of cirrhosis (age >18 years ) who will be admitted to internal medicine department or will be admitted to intermediate care unit

• willing and agree to be included in the study

Exclusion Criteria:

• patients without evidence of cirrhosis

• cirrhotic patients whom -younger than 18 years old

  • have diabetic ketoacidosis
  • with acute coronary syndrome
  • with fulminant liver failure
  • with heart failure
  • with organ transplantation
  • when arterial blood gases not be available
  • patient refusal
  • patient with HCC

the study protocol will be approved by ethical committee of sohag university of medicine written informed consent will be obtained from all participants