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This study is a safety and feasibility study to determine if ultrasound guided radiofrequency ablation of parotid Warthin's tumor under local anesthesia is a safe and effective procedure compared to Parotidectomy while using less resources.
Radiofrequency ablation is minimally invasive and is used in benign disease, including thyroid nodules, head and neck nodules, and vascular malformations, as well as some malignant tumors. For patients unable to or unwilling to undergo surgical resection, real-time ultrasound guided radiofrequency ablation for parotid Warthin's Tumor would be a further option besides observation alone.
Twenty patients with Warthin's tumor from the ENT Head and Neck Surgery out-patient clinic at Prince of Wales Hospital will be recruited. The patient will first be asked if they wanted intervention for their condition of Warthin's Tumor. Parotidectomy will first be offered. If the patient opted for intervention but declines parotidectomy, then ultrasound guided RFA will be offered.
The 2019 - 2020 Parotidectomy for Warthin's tumor internal audit will be used as a historical comparison to the ultrasound guided RFA group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| RFA Warthins Tumor Group | Experimental | Group of patients who will under RFA for Warthin's tumor. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasound-guided Radiofrequency Ablation of Parotid Warthin's Tumor | Procedure | The Procedure
|
| Measure | Description | Time Frame |
|---|---|---|
| Volume reduction of Warthin's tumor compared to baseline | Comparison of ultrasound volumetric scan results from 45 weeks post-operative to baseline | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Cost and resources | Total cost of the procedure including all related costs | 1 year |
| Length of in-patient stay | Total number of in-patient stays recorded as number of days |
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Inclusion Criteria:
18 years and older
Ultrasound scan findings:
Tumor is clinically palpable tumor
Symptomatic disease with facial asymmetry and cosmetic concerns
Diagnosis confirmed by fine needle aspiration x 2
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| David CM Yeung, MBChB | Chinese University of Hong Kong | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Prince of Wales Hospital | Hong Kong | Select | 00000 | Hong Kong |
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Safety and Feasibility Study
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| 1 week |
| Operating time | Time required for the procedure recorded as minutes | 1 day |
| Perioperative and post-operative complications | Perioperative and post-operative complications in immediate post-operatively and during the follow-up period | 1 year |
| Cosmetic score | A subjective score of cosmesis graded by the patient on a scale of 1 - 4, with the higher score having worse cosmetic outcomes | 1 year |
| Visual analogue scale for pain | Collected immediately post-operatively on a scale of 1 - 10, with the higher score being more painful | 1 day |
| Visual analogue scale for patient satisfaction | Subjectively graded by the patient on a scale of 1-10 for outcome satisfaction, with the higher score being more satisfactory | 1 year |