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Even after adequate TME with grade III mesorectal grading, local recurrence remains a possible event. Several studies investigated different parameters and assessed their predictive power in regards to local recurrence after TME. These parameters included a variety of patient-related, tumor-related, and treatment-related factors. A recent meta-analysis reviewed the current literature for the predictors of local recurrence after TME for rectal cancer and developed a prognostic scoring system, the PREDICT score.
The present study aimed to validate the PREDICT scoring system by applying it to a prospective cohort of patients with rectal cancer who underwent curative TME in three
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with recurrence after TME | Patients who developed local recurrence after TME of rectal cancer |
| |
| Patients without recurrence after TME | Patients who did not develop local recurrence after TME of rectal cancer |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PREDICT score | Diagnostic Test | Predictive score for local recurrence after TME for rectal cancer that includes 8 parameters |
|
| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity of PREDICT score | The ability of the score to predict actual cases of recurrence after TME | 36 months after surgery |
| Specificity of PREDICT score | The ability of the score to predict patients who did not experience recurrence after TME | 36 months after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with stage I-III rectal cancer who underwent surgery with curative intent
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| Name | Affiliation | Role |
|---|---|---|
| Sameh H Emile, M.D., FACS | Mansoura University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mansoura university hospital | Al Mansurah | Dakahlia Governorate | 35516 | Egypt |
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| ID | Term |
|---|---|
| D012004 | Rectal Neoplasms |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
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| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |