Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
SARS-COV-2 infection is responsible for a potentially severe primarily respiratory infection called COVID19. A large proportion of patients, in particular in severe forms, present with thrombotic manifestations (DVT, EP, stroke, thrombosis of dialysis circuits, etc.). A significant proportion is also a carrier of circulating anticoagulant (ACC or LA), making it possible to suggest a diagnosis of APS. This type of autoantibody results in a spontaneous prolongation of the TCA uncorrected by a control serum therefore is quickly diagnosed using standard hemostasis The objective of this study is to describe the diagnosis of thrombotic complications in COVID19 patients presenting a positive lupus anticoagulant type test (LA) or aPL and the associated clinical and biological elements that may have favored thrombosis.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Retrospective study of thrombotic complications in a cohort of COVID patients with a circulating anticoagulant | Files analysed retrospectively from March 01, 2020 to May 31, 2019 will be examined] |
Not provided
Not provided
Inclusion criteria:
Exclusion criteria:
Not provided
Not provided
Not provided
Not provided
Major patient infected with Covid-19, with a documented infection, having presented a documented thrombosis (arterial or venous), with an LA or aPL in the thrombosis assessment
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anne-Sophie Korganow, MD, PhD | Contact | 33 3 69 55 05 21 | Anne-sophie.Korganow@chru-strasbourg.fr | |
| Saïd CHAYER, PhD, HDR | Contact | said.chayer@chru-strasbourg.fr |
| Name | Affiliation | Role |
|---|---|---|
| Anne-Sophie Korganow, MD, PhD | Service de Médecine Interne et d'Immunologie Clinique - Hôpitaux Universitaires de Strasbourg | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Médecine Interne et d'Immunologie Clinique - Hôpitaux Universitaires de Strasbourg | Recruiting | Strasbourg | 67091 | France |
Not provided
| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D016736 | Antiphospholipid Syndrome |
| D001327 | Autoimmune Diseases |
| D013927 | Thrombosis |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
Not provided
Not provided
Not provided
Not provided
Not provided
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D007154 | Immune System Diseases |
| D016769 | Embolism and Thrombosis |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |