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The present study aimed to assess the diagnostic performance of ultrasound-guided endobronchial intra-nodal miniforceps biopsy (EBUS-MFB) in the diagnosis of "de novo" mediastinal lymphoma.
Every patients will be sampled using both EBUS-MFB and the standard of care EBUS-TBNA (transbronchial needle aspiration).
It is a monocentric investigation. Pathologist will not know the way of sampling while analysing the samples
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| EBUS-MFB and EBUS-TBNA | Experimental | patient will have both TBNA and MFB in the same operating time |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endobronchial ultrasound guided miniforceps biopsy and transbronchial needle aspiration | Device | Mediastinal node is sampled using three path of classic ultrasound guided transbronchial needle aspiration (EBUS-TBNA). A reduce size forceps is then inserted inside the mediastinal node via the duc EBUS-TBNA made and biopsies (EBUS-MFB) are made using real time ultrasound guidance. |
| Measure | Description | Time Frame |
|---|---|---|
| positivity of the procedure in Diagnosis and Subtyping of lymphoma | a sample wil be considered positive if it allows the clinical management of the patient, without additional sampling required. | up to 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| every adverse effect related to the procedure | infectious process related to the procedure, hemoptysis over 50cc, worsening of respiratory status requiring hospitalization | up to 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Romain M Magnier, MD | Contact | 0291069029 | +33 | magnier-r@chu-caen.fr |
| Pierre M Cuchet, MD | Contact | 0231063029 | +33 | cuchet-p@chu-caen.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CaenUH | Recruiting | Caen | Normandy | 14000 | France |
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| ID | Term |
|---|---|
| D008223 | Lymphoma |
| ID | Term |
|---|---|
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D008232 | Lymphoproliferative Disorders |
| D008206 | Lymphatic Diseases |
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pathologist do not know the technique of sampling used when analysing slides.
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|
| D006425 | Hemic and Lymphatic Diseases |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |