Pulmonary Function in Patients Recovering From COVID19 Infection : a Pilot Study

Pulmonary Function in Patients Recovering From COVID19 Infection : a Pilot Study

The current state of knowledge shows the presence of respiratory sequelae after acute infection with COVID-19 and the importance of these long-term respiratory dysfunctions have to be determined.

Aim of our study is describe diaphragmatic amplitude using diaphragm ultrasonography in patients recovering from SARS-CoV-2 pneumonia at 3 and 6 months after the acute episode.

patients with confirmed COVID-19 who had been discharged from CHRU Hospital in Limoges (France) will be included to follow the impact of severe acute respiratory syndrom coronavirus 2 on pulmonary function, diaphragm function and exercice capacity. Surviving patients will be evaluated at 3 and 6 months after hospital discharge. The assesment will include diaphragm ultrasonography, spirometry (FEV1,FVC), carbon monoxide transfert (TLCO adjusted for haemoglobin), inspiratory an expiratory respiratory muscle strength (Pimax and Pemax) and 6 minutes walk distance (6MWD).The main outcome will be diaphragm excursion assessed by ultrasound.

Inclusion Criteria:

• SARS-CoV-2 infection proven by RT-PCR.
• Patient hospitalised for the management of SARS-CoV-2 infection and included 3 months after the end of his hospitalisation at the CHU of Limoges.
• Patient of legal age.
• Patient affiliated to a social security regime.
• Patient having given informed consent

Exclusion Criteria:

• Known pregnancy.
• Patients who are contraindicated to perform the 6-minute walk test.
• Patients unable to understand or adhere to the protocol.
• Patients deprived of liberty.
• Patients under court order, tutorship or curatorship.
• Minor patients