A Study of Near-Infrared Fluorescence Imaging With ICG During Reconstructive Gynecologic Surgery

Near-infrared FluORescencE Assessment of Myocutaneous Flap Microperfusion for Gynecologic RecONstrucTion (FOREFRONT): A Pilot Study

The objective of this study is to assess whether Near-Infrared Fluorescence/NIR Imaging perfusion alters intraoperative management of the flap or of the participant wound bed.

Inclusion Criteria:

• Women undergoing a pelvic reconstruction procedure after radical gynecologic surgery for any indication at MSK.
• Age ≥18 years.

Exclusion Criteria:

• Women with hepatic dysfunction as evidenced by elevated transaminases (two times the upper limit of normal).
• Women with a history of cirrhosis or other chronic liver disease.
• Women with a documented severe or life threatening allergy to iodine.
• Women with an allergy to ICG or severe allergy to iodinated contrast.
• Women undergoing any free flap (non-pedicled) reconstruction.