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| Name | Class |
|---|---|
| Médipôle Lyon-Villeurbanne | OTHER |
| Centre Hospitalier Memorial France Etats-Unis | OTHER |
| Centre Hospitalier de Valence | OTHER |
| Centre Hospitalier de Troyes |
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The purpose of the study is to describe medical care strategies implemented by healthcare establishments for patients affected by COVID-19
Coronavirus infection (SARS-Cov2), very contagious, is benign in the most cases but can be complicated by an acute respiratory distress syndrome, for which an invasive mechanical ventilation in resuscitation is necessary with an important mortality rate. This infection is about an important health crisis with a fast saturation of the health system.
In front of the novelty of this virus, any effective treatment has been demonstrated in humans and researches have accelerated as this pandemic continues.
First available results, in chinese population, have not demonstrated superiority of the Lopinavir/Ritonavir association versus standard care (Cao et al. 2020). In a randomized study in 62 chinese patients, Chen et al. seems to find a clinical efficacy of the Hydroxychloroquine compared to placebo. Gautret et al. has also found a decreased viral load in nasopharyngeal swabs in patients affected by COVID-19, treated by Hydroxychloroquine and by the association of Hydroxychloroquine-Azythromycine. However, these preliminary results doesn't allow to conclue on the efficacy against COVID-19.
Currently, any treatment in particular is recommanded for patients affected by COVID-19. Randomized studies on a larger scale and greater rigor at national and european level are in process to determine the efficacy of several treatments.
Pending results of these studies, healthcare establishments had to adapt and strategize to take care their patients. These strategies have rapidely evolved during this pandemy, in terms of the therapeutic clinical studies opening, the acquisition of new knowledges on COVID-19, and treatments.
Screening : All patients with a COVID-19 diagnosis who have been treated in 2020 in participant establishements will be included in the HOPICOV study.
Enrolment : On discharge from hospital, an information notice will be delivered to the patient (or at his close relative / his legal guardian) to allow him to exert his right to oppose his collection data identified as part of the treatment. Otherwise, this information might be send by letter after his discharge.
All participating centers will be encouraged to enter data as things progress to allow interim analysis and scientific communication.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Data collection | Other | Some data will be collected for all patients included :
Evolution of French recommendations and the publication of scientific articles |
| Measure | Description | Time Frame |
|---|---|---|
| Describe management strategies implemented by healthcare establishments for patients with covid-19, depending on the evolution of scientific knowledge and recommendations for specific treatments. | The use of specific treatments or specific care in COVID unit, inclusion in clinical trials, will be combined to report the evolution of French recommendations and scientific literature around the COVID-19. | During the hospitalization |
| Measure | Description | Time Frame |
|---|---|---|
| Describe management strategies to take care depending on the patient | Specific and non specific administered treatments, inclusion in clinical trials, depending on the patients' age, symptoms at admission, comorbidities (including the presence of renal failure, unbalanced diabetes or heart disorder based on laboratory criteria and ECG) will be combined to describe different management strategies to take care depending on the patient. |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patient diagnosed for COVID-19 infection and hospitalized in healthcare establishment in 2020
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Center Emile Roux | Le Puy-en-Velay | 43012 | France |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| ID | Term |
|---|---|
| D003625 | Data Collection |
| ID | Term |
|---|---|
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
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| OTHER |
| Groupe Hospitalier de la Rochelle Ré Aunis | OTHER |
| Centre Hospitalier William Morey - Chalon sur Saône | OTHER |
| Centre Hospitalier de Saint-Malo | UNKNOWN |
| Centre Hospitalier Intercommunal de Mont de Marsan | UNKNOWN |
| Centre Hospitalier Intercommunal de Poissy / Saint-Germain | UNKNOWN |
| Centre Hospitalier de Dax | UNKNOWN |
| Centre Hospitalier Public du Cotentin | UNKNOWN |
| Centre Hospitalier Henri Duffaut - Avignon | OTHER |
| Boulogne sur Mer Hospital Center | OTHER |
| Centre Hospitalier Louis Pasteur, Chartres | UNKNOWN |
| Centre Hospitalier de Montauban | OTHER |
| Centre Hospitalier de Saint-Brieuc | OTHER |
| Groupe Hospitalier Aube Marne | UNKNOWN |
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| During the hospitalization |
| Compare patients' clinical course who received different management strategies | Comparison of hospitalization time (days), time between the onset and the end of symptoms (days), passage in intensive care and patients' vital status, according to the treatments received (non-specific / standard versus the different specific treatments administered off-label within the framework of clinical trials or not) will be combined to compare the patients' clinical course who received different management strategies | During the hospitalization |
| Evaluate the cost of the care | Costs of specific treatments | During the hospitalization |
| Evaluate the effectiveness of the care | Hospitalization time and survival status will be combined to evaluate the effectiveness of the care | During the hospitalization |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |