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| Name | Class |
|---|---|
| Asua, Inc | UNKNOWN |
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An Artificial Intelligence platform to develop an app which improves compliance in periodontal treatments
To develop the accuracy of an AI-determined decision-making process for compliance score (CS) assignment, to assess clinical efficacy, and develop patient reported outcomes of AI-facilitated communication / education on a subject's oral health behaviors over successive maintenance visits.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Artificial Intelligence Application | Behavioral | AI application through smart phone |
| Measure | Description | Time Frame |
|---|---|---|
| To identify the input variables the AI utilizes to arrive at CS assignment and message selection for subject interaction via DDH app | Digital hygiene app will provide messages to subjects via their smartphone regarding their their lst maintenance appointment and throughout the study. | through study completion, approximately 7 months |
| Measure | Description | Time Frame |
|---|---|---|
| Compliance Score Accuracy | the increase the compliance score ant 3 and 6 months after subject begins use of the AI app | 6 months |
| change in recession | number of subjects with a lesser degree of recession from baseline to end of study due to increased subject compliance |
| Measure | Description | Time Frame |
|---|---|---|
| PRO | PRO for subject experience using the AI app system | 6 months |
| Subject demographics | determination of demographics on subjects with periodontal disease |
Inclusion Criteria:
Exclusion Criteria:
Subjects who do not own or are incapable of interacting with a smart phone or device
Subjects who are incapable of operating an application on a smart phone or device
Subjects who are not compliant with periodontal maintenance / recall intervals (Based on Wilson's classification as any lack of compliance with their recommended maintenance interval- therefore exclude subjects who demonstrate erratic compliance or noncompliance)18
Subjects who require active periodontal therapy during the study
Subjects who are on immunosuppressive medications, chemotherapy, or radiation therapy which would adversely affect their periodontal stability.
Subjects participating in other clinical studies involving therapeutic intervention (either medical or dental).
Subjects, who in the opinion of the investigator, for any reason other than those listed above, will not be able to complete the study per protocol.
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Exclusion Criteria:
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50 subjects minimum, 18-75 years of age, treated for periodontitis in a private practice who are currently following a periodontal maintenance regimen.
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| Name | Affiliation | Role |
|---|---|---|
| Rick Heard, DDS | The McGuire Institute | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Metro West Orthodontics & Periodontics | La Vista | Nebraska | 68128 | United States | ||
| Perio Health Professionals |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Shapiro SC. Encyclopedia of Artificial Intelligence. New York: Wiley; 1992. | ||
| 30369809 | Background | Park WJ, Park JB. History and application of artificial neural networks in dentistry. Eur J Dent. 2018 Oct-Dec;12(4):594-601. doi: 10.4103/ejd.ejd_325_18. | |
| Background | Jackson P. Introduction to Expert Systems. London: Addison Wesley; 1986 | ||
| 20949757 |
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| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| ID | Term |
|---|---|
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| 6 months |
| change in probing depth | number of subjects with a lesser probing depth from baseline to end of study due to increased subject compliance | 6 months |
| change in clinical attachment level | number of subjects with improved clinical attachment level due to increased subject compliance | 6 months |
| change in gingival inflammation | number of subjects with a reduction in gingival inflammation due to increased subject compliance | 6 months |
| decrease mobility | number of subjects showing a decreased degree of tooth mobility due to increased subject compliance | 6 months |
| 6 months |
| AI generated surveys | survey to determine subjects progress, risk disease, oral hygiene needs, coping and goal setting abilities, and compliance | 6 months |
| Hygienist In office subject survey | to measure subjects hygiene and other life events (e.g. work stress) | 6 months |
| Houston |
| Texas |
| 77063-7229 |
| United States |
| Background |
| Khanna S. Artificial intelligence: contemporary applications and future compass. Int Dent J. 2010 Aug;60(4):269-72. |
| 19905850 | Background | Xie X, Wang L, Wang A. Artificial neural network modeling for deciding if extractions are necessary prior to orthodontic treatment. Angle Orthod. 2010 Mar;80(2):262-6. doi: 10.2319/111608-588.1. |
| 19592958 | Background | Kim EY, Lim KO, Rhee HS. Predictive modeling of dental pain using neural network. Stud Health Technol Inform. 2009;146:745-6. |
| 31120578 | Background | Reddy MS, Shetty SR, Shetty RM, Vannala V, Sk S. Future of periodontics lies in artificial intelligence: Myth or reality? J Investig Clin Dent. 2019 Nov;10(4):e12423. doi: 10.1111/jicd.12423. Epub 2019 May 23. No abstract available. |
| 3295181 | Background | Wilson TG Jr, Glover ME, Malik AK, Schoen JA, Dorsett D. Tooth loss in maintenance patients in a private periodontal practice. J Periodontol. 1987 Apr;58(4):231-5. doi: 10.1902/jop.1987.58.4.231. |
| 16460248 | Background | Miyamoto T, Kumagai T, Jones JA, Van Dyke TE, Nunn ME. Compliance as a prognostic indicator: retrospective study of 505 patients treated and maintained for 15 years. J Periodontol. 2006 Feb;77(2):223-32. doi: 10.1902/jop.2006.040349. |
| 8832477 | Background | McGuire MK, Nunn ME. Prognosis versus actual outcome. III. The effectiveness of clinical parameters in accurately predicting tooth survival. J Periodontol. 1996 Jul;67(7):666-74. doi: 10.1902/jop.1996.67.7.666. |
| 25495962 | Background | Needleman I, Nibali L, Di Iorio A. Professional mechanical plaque removal for prevention of periodontal diseases in adults--systematic review update. J Clin Periodontol. 2015 Apr;42 Suppl 16:S12-35. doi: 10.1111/jcpe.12341. |
| 25639948 | Background | Tonetti MS, Eickholz P, Loos BG, Papapanou P, van der Velden U, Armitage G, Bouchard P, Deinzer R, Dietrich T, Hughes F, Kocher T, Lang NP, Lopez R, Needleman I, Newton T, Nibali L, Pretzl B, Ramseier C, Sanz-Sanchez I, Schlagenhauf U, Suvan JE. Principles in prevention of periodontal diseases: Consensus report of group 1 of the 11th European Workshop on Periodontology on effective prevention of periodontal and peri-implant diseases. J Clin Periodontol. 2015 Apr;42 Suppl 16:S5-11. doi: 10.1111/jcpe.12368. |
| 30997690 | Background | Asimakopoulou K, Nolan M, McCarthy C, Newton JT. The effect of risk communication on periodontal treatment outcomes: A randomized controlled trial. J Periodontol. 2019 Sep;90(9):948-956. doi: 10.1002/JPER.18-0385. Epub 2019 Apr 17. |
| 31562778 | Background | Amerio E, Mainas G, Petrova D, Giner Tarrida L, Nart J, Monje A. Compliance with supportive periodontal/peri-implant therapy: A systematic review. J Clin Periodontol. 2020 Jan;47(1):81-100. doi: 10.1111/jcpe.13204. Epub 2019 Nov 13. |
| 25682859 | Background | Asimakopoulou K, Newton JT, Daly B, Kutzer Y, Ide M. The effects of providing periodontal disease risk information on psychological outcomes - a randomized controlled trial. J Clin Periodontol. 2015 Apr;42(4):350-5. doi: 10.1111/jcpe.12377. Epub 2015 Mar 24. |
| 25639708 | Background | Newton JT, Asimakopoulou K. Managing oral hygiene as a risk factor for periodontal disease: a systematic review of psychological approaches to behaviour change for improved plaque control in periodontal management. J Clin Periodontol. 2015 Apr;42 Suppl 16:S36-46. doi: 10.1111/jcpe.12356. |
| 21722952 | Background | Free C, Knight R, Robertson S, Whittaker R, Edwards P, Zhou W, Rodgers A, Cairns J, Kenward MG, Roberts I. Smoking cessation support delivered via mobile phone text messaging (txt2stop): a single-blind, randomised trial. Lancet. 2011 Jul 2;378(9785):49-55. doi: 10.1016/S0140-6736(11)60701-0. |
| 6384465 | Background | Wilson TG Jr, Glover ME, Schoen J, Baus C, Jacobs T. Compliance with maintenance therapy in a private periodontal practice. J Periodontol. 1984 Aug;55(8):468-73. doi: 10.1902/jop.1984.55.8.468. |
| 29926952 | Background | Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Periodontol. 2018 Jun;89 Suppl 1:S159-S172. doi: 10.1002/JPER.18-0006. |
| Background | Miller SC. Textbook of Periodontia: Philadelphia, Blakiston; 1938 |
| 4500182 | Background | O'Leary TJ, Drake RB, Naylor JE. The plaque control record. J Periodontol. 1972 Jan;43(1):38. doi: 10.1902/jop.1972.43.1.38. No abstract available. |