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This research project aims at evaluating the effect of various ketone precursors and their formulations on blood ketone level after oral intake. Evaluation of the GI tolerability of the various formula will be also evaluated.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ketone Precursor Formula 1 | Active Comparator | Formula 1 (in each cycle, up to 4 formula will be tested) Ketone precursors formula (powder to reconstitute in drinking water, or in a ready-to-drink format). |
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| Ketone Precursor Formula 2 | Active Comparator | Ketone precursors formula (powder to Reconstitute in drinking water, or in a ready-to-drink format). |
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| Ketone Precursor Formula 3 | Active Comparator | Ketone precursors formula (powder to Reconstitute in drinking water, or in a ready-to-drink format) |
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| Ketone Precursor Formula 4 | Active Comparator | Ketone precursors formula (powder to Reconstitute in drinking water, or in a ready-to-drink format), or placebo |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| different ketogenic formulae | Dietary Supplement | The research product may be in a form of powder to reconstitute or in a ready-to-drink format. |
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| Measure | Description | Time Frame |
|---|---|---|
| Ketone Plasma Kinetics After Oral Intake of Different Ketogenic Formulae | Incremental area under the curve of total blood ketones | 0 (baseline) to 4 hours after products consumption |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pamela Sun | Société des Produits Nestlé (SPN) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nestlé Clinical Innovation Lab | Lausanne | Switzerland |
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Each testing cycle design will be either a complete or partial cross-over.
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