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These are the characteristics of the project:
Monocentric:
Double blind randomized and crossover: you will test all the 3 products in random order.
This study will be randomized, double blind, placebo-controlled, single-center, and 3x3 crossover in design. Eligible participants will be randomized to receive the below products in single dose and in different random sequence, as determined by the randomization system
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| novel alpha glucan | Experimental | 50g novel alpha glucan dissolved in 300ml water |
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| glucose syrup | Active Comparator | 50g dissolved in 300ml water |
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| Inulin | Active Comparator | 15g Inulin dissolved in 300ml water |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Drinkable solution | Dietary Supplement | the volunteer will consume the volume 300 ml of water with |
|
| Measure | Description | Time Frame |
|---|---|---|
| Glucose concentration post ingestion of a test product | postprandial glycemic response | 180 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| insulin response post ingestion of a test product | postprandial insulin response | 180 minutes |
| intestinal hydrogen production as measured by breath hydrogen | postprandial breath hydrogen |
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Inclusion Criteria:
Healthy status (based on anamnesis) Body mass index (BMI) between 18.5 and 29.9 kg/m2 Able to understand and sign informed consent form.
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Innovation Lab | Lausanne | Switzerland |
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3X3
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| 240 minutes |