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The aim of the study is that evaluation of basic and accessory respiratory muscles and their relationship of six minute walk test in patient with pulmonary arterial hypertension (PAH)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients | Maximal mouth pressure will be evaluated for determine respiratory muscle strength, m. pectoralis, m. serratus anterior, m. sternocloideumasteoideus and quadriceps muscles strengths will be measured to evaluate accessory respiratory muscle strength, London chest activity of daily living scale will be done for assessment of dyspnea and six minute walk test will be used for determination of functionally capacity |
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| Control group | Maximal mouth pressure will be evaluated for determine respiratory muscle strength, m. pectoralis, m. serratus anterior, m. sternocloideumasteoideus and quadriceps muscles strengths will be measured to evaluate accessory respiratory muscle strength, London chest activity of daily living scale will be done for assessment of dyspnea and six minute walk test will be used for determination of functionally capacity |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| patient assessment | Diagnostic Test | subjective and objective measurement will be performed in patients with PAH |
|
| Measure | Description | Time Frame |
|---|---|---|
| pectoralis muscle strength | pectoralis muscle strength will be evaluated with hand held dynamometers according to muscle test technique | 15 minute |
| serratus anterior muscle strength | Serratus anterior muscle strength will be evaluated with hand held dynamometers according to muscle test technique | 15 minutes |
| sternocleidomasteoideus muscle strength | sternocleidomasteoideus muscle strength will be evaluated with hand held dynamometers according to muscle test technique | 15 minutes |
| Respiratory mouth pressure | Respiratory mouth pressure will be measured to determine maximally inspiratory pressure and maximally expiratory pressure according to ATS/ERS guidelines. | 15 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Six Minute Walk Test (6MWT) | Six minute walk test will be performed to evalute functionally exercise capacity according to ATS/ERS guidelines | 30 minutes |
| Dyspnea assessment | London Chest Activity of Daily Living Scale will be used to sensation of dyspnea during activity of daily living.The scale consists of four domains: self-care (four items), domestic (six items), physical (two items) and leisure (three items). In total, the scale consisting of 15 items scored of 0 to 5. 0 means that "I wouldn't do anyway" and 5 means that "Someone else does it for me". Higher values indicate greater limitation due to the dyspnea |
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Inclusion Criteria:
Exclusion Criteria:
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patient group will be chosen among the admitted to clinic control group will consist of invited volunteers
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| Name | Affiliation | Role |
|---|---|---|
| Habibe DURDU | Giresun University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul university-cerrahpasa cardiology institute | Istanbul | Haseki | 34096 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26401245 | Background | Panagiotou M, Peacock AJ, Johnson MK. Respiratory and limb muscle dysfunction in pulmonary arterial hypertension: a role for exercise training? Pulm Circ. 2015 Sep;5(3):424-34. doi: 10.1086/682431. | |
| 32028638 | Background | Riou M, Pizzimenti M, Enache I, Charloux A, Canuet M, Andres E, Talha S, Meyer A, Geny B. Skeletal and Respiratory Muscle Dysfunctions in Pulmonary Arterial Hypertension. J Clin Med. 2020 Feb 3;9(2):410. doi: 10.3390/jcm9020410. |
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| ID | Term |
|---|---|
| D065627 | Familial Primary Pulmonary Hypertension |
| D004417 | Dyspnea |
| ID | Term |
|---|---|
| D006976 | Hypertension, Pulmonary |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D012120 | Respiration Disorders |
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| 20 minutes |
| D012818 |
| Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |