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| ID | Type | Description | Link |
|---|---|---|---|
| CIV-21-05-036744 | Other Identifier | Swedish Medical Products Agency |
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| Name | Class |
|---|---|
| University Hospital, Umeå | OTHER |
| Sundsvall Hospital | OTHER |
| Sahlgrenska University Hospital | OTHER |
| Västernorrland County Council, Sweden |
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Acute onset vertigo is common and entails much suffering with persisting symptoms at 3 months after onset in up to half of those afflicted. Vestibular rehabilitation to aid recovery is not readily available. The purpose of this study is to investigate the effects on vertigo symptoms of a 6-week online vestibular rehabilitation tool compared with standard care (written instructions leaflet) after acute onset vertigo.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group | Experimental |
| |
| Control group | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Online vestibular rehabilitation tool | Device | For those randomized to the intervention group, a 6 weeks duration vestibular rehabilitation will be delivered using an online tool (YrselTräning) |
| Measure | Description | Time Frame |
|---|---|---|
| The between group mean Vertigo Symptom Scale Short Form (VSS-SF) score difference | VSS-SF uses a five-point Likert scale: 0 (never), 1 (a few times), 2 (several times), 3 (quite often [every week]), and 4 (very often [most days]). The score ranges from 0 to 60. A higher score indicates worse symptoms. | 6 weeks after vertigo onset |
| Measure | Description | Time Frame |
|---|---|---|
| The between groups mean Dizziness Handicap Inventory (DHI) score | The Dizziness Handicap Inventory (DHI) uses a three-point scale to rate each item: 0 (no), 2 (sometimes), and 4 (always). The score ranges from 0 to 100. A higher overall score indicates more severe handicap. | 6 weeks and 3 months after vertigo onset |
| Measure | Description | Time Frame |
|---|---|---|
| The proportion of participants who has experienced falls/fractures since study start | 6 weeks, 3 months and 12 months | |
| The number of falls/fractures in each study arm | 6 weeks, 3 months and 12 months |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jonatan Salzer, MD, PhD | Umeå University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Södra Älvsborg Hospital | Borås | Sweden | ||||
| Sahlgrenska University Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35710448 | Background | Surano S, Grip H, Ohberg F, Karlsson M, Faergemann E, Bjurman M, Davidsson H, Ledin T, Lindell E, Mathe J, Tjernstrom F, Tomanovic T, Granasen G, Salzer J. Internet-based vestibular rehabilitation versus standard care after acute onset vertigo: a study protocol for a randomized controlled trial. Trials. 2022 Jun 16;23(1):496. doi: 10.1186/s13063-022-06460-0. | |
| 39928092 |
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| ID | Term |
|---|---|
| D014717 | Vertigo |
| ID | Term |
|---|---|
| D015837 | Vestibular Diseases |
| D007759 | Labyrinth Diseases |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
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| ID | Term |
|---|---|
| D059039 | Standard of Care |
| ID | Term |
|---|---|
| D019984 | Quality Indicators, Health Care |
| D011787 | Quality of Health Care |
| D006298 | Health Services Administration |
| D017530 | Health Care Quality, Access, and Evaluation |
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| OTHER_GOV |
| Södra Älvsborg Hospital | OTHER |
| Karolinska University Hospital | OTHER |
| University Hospital, Linkoeping | OTHER |
| Sunderby Hospital | OTHER |
| Capio Sankt Görans Hospital | OTHER |
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| Standard care (written instructions leaflet) | Other | For those randomized to the control group, a 6 weeks duration standard vestibular rehabilitation will be delivered using a written instructions leaflet |
|
| The between groups changes in timed 25-foot walk test (T25-FW)); body sway during standing and walking; and the mobility |
| From baseline to 6 weeks and 3 months |
| The between groups changes in video head impulse test (vHIT, site-dependent) | 6 weeks and 3 months after vertigo onset |
| The between groups changes in video head impulse test (vHIT, site-dependent) measured lateral canal VOR gain and saccades | From baseline to 6 weeks and 3 months |
| The between groups mean vertigo symptom scale short form (VSS-SF) score | VSS-SF uses a five-point Likert scale: 0 (never), 1 (a few times), 2 (several times), 3 (quite often [every week]), and 4 (very often [most days]). The score ranges from 0 to 60. A higher score indicates worse symptoms. | 12 months after vertigo onset |
| The between group pedometer-derived mean weekly number of steps walked since last visit | 3 months after vertigo onset |
| The between groups mean number of weekly training sessions | 6 weeks after vertigo onset |
| Register-based search for health economic effects on all levels of care (primary, specialized) and society (sick leave) | 12 months |
| The difference in kinematic output between measurement systems (i.e., multi-sensor and mobile app) | Three months after symptom onset |
| The reliability of the Swedish VSS-SF translation | Six weeks after symptom onset |
| The frequency of BPPV at 6 weeks and 3 months after AVS onset using a BPPV specific questionnaire and positional nystagmus tests | 6 weeks and 3 months after vertigo onset |
| Gothenburg |
| Sweden |
| University Hospital Linköping | Linköping | Sweden |
| Sollefteå Hospital | Sollefteå | Sweden |
| Sunderby Hospital | Södra Sunderbyn | Sweden |
| Capio Sankt Görans Hospital | Stockholm | Sweden |
| Karolinska University Hospital | Stockholm | Sweden |
| Sundsvall Hospital | Sundsvall | Sweden |
| University Hospital Umeå | Umeå | Sweden |
| Surano S, Faergemann E, Granasen G, Salzer J. The reliability and validity of the Swedish translation of the Vertigo Symptom Scale - short form in a cohort with acute vestibular syndrome. Ann Med. 2025 Dec;57(1):2457517. doi: 10.1080/07853890.2025.2457517. Epub 2025 Feb 10. |
| 42284306 | Derived | Surano S, Lindell E, Mathe J, Davidsson H, Tomanovic T, Bjurman M, Faergemann E, Ledin T, Rostmark A, Grip H, Ohberg F, Granasen G, Salzer J. Internet-based vestibular rehabilitation versus written instructions after acute vertigo: A randomised controlled trial. PLoS One. 2026 Jun 12;21(6):e0351092. doi: 10.1371/journal.pone.0351092. eCollection 2026. |
| D009461 |
| Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |