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Principal Investigator left the institution.
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| Name | Class |
|---|---|
| American Neurogastroenterology and Motility Society | OTHER |
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The purpose of this research is to further study the relationship between gastroparesis (GP) (a condition in which the stomach cannot empty itself of food in a normal fashion) and functional dyspepsia (FD) (frequent symptoms of indigestion that have no obvious cause).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gastroparesis | Experimental | Participants in this group are children diagnosed with gastroparesis per gastric emptying scintigraphy. Participants will be receiving a gastric emptying breath test three times over the course of 6 months and an ultrasound of the stomach once. |
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| Dyspepsia | Experimental | Participants in this group are children diagnosed with functional dyspepsia per gastric emptying scintigraphy. Participants will be receiving a gastric emptying breath test three times over the course of 6 months and an ultrasound of the stomach once. |
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| Healthy Controls | Experimental | Participants in this group are children that do not have gastroparesis, functional dyspepsia, or any other gastroenterology condition. Participants will be getting an ultrasound once. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gastric emptying breath test | Other | The gastric emptying breath test is used to diagnose gastroparesis. Participants ingest spirulina in a meal and samples are taken every 45 minutes for 4 hours. |
| Measure | Description | Time Frame |
|---|---|---|
| Gastric emptying rate | As measured by the spirulina breath test | up to 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of food retained in the stomach | Fundic accommodation will be reported as the percentage of food retained in the fundus using an ultrasound before and after meal ingestion. | Day 1 |
| Pediatric Cardinal Symptoms Questionnaire Scores |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Liz Febo-Rodriguez, MD | University of Miami | Principal Investigator |
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| ID | Term |
|---|---|
| D018589 | Gastroparesis |
| D004415 | Dyspepsia |
| ID | Term |
|---|---|
| D013272 | Stomach Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010243 | Paralysis |
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| Stomach ultrasound | Other | Ultrasound of the fundus of the stomach will be done immediately after ingestion of the test meal, at 15 minutes, and at 30 minutes. |
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The pediatric symptoms questionnaires has a total score ranging from 0-600. Higher score means worse symptoms.
| Up to 6 months |
| D009461 |
| Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012817 | Signs and Symptoms, Digestive |