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| ID | Type | Description | Link |
|---|---|---|---|
| NCI-2019-00862 | Registry Identifier | CTRP (Clinical Trial Reporting Program) | |
| 2018-0216 | Other Identifier | M D Anderson Cancer Center |
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| Name | Class |
|---|---|
| National Cancer Institute (NCI) | NIH |
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This trial studies the development of patient-specific computational walking models to improve the surgical planning and rehabilitation treatment of patients with pelvic sarcomas. Every pelvis and pelvic sarcoma are different, and the orthopedic oncologist faces significant challenges when removing a tumor from the complex anatomy of the pelvis. These challenges make it difficult to achieve excellent oncological and functional outcomes together. Computational walking models may be used to predict the best combination of surgical methods and how to implement them to maximize each patient's post-surgery walking function.
PRIMARY OBJECTIVES:
I. To develop patient-specific computational walking models to predict the optimal combination of pelvic sarcoma surgical and rehabilitation decisions that will maximize each patient's post-surgery walking function.
II. To collect experimental movement and imaging data prospectively and retrospectively from individuals who have already received, or are going to receive, a type I or type II hemipelvectomy.
III. To use the data to develop computational modeling and simulation methodologies that can predict an individual patient's post-surgery walking function given pre-surgery movement and imaging data and the surgical decisions made by the surgeon.
OUTLINE:
Patients undergo walking function assessment using optical motion capture and bi-plane dynamic X-ray imaging pre- and post-hemipelvectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Supportive care (walking function test, X-ray) | Experimental | Patients undergo walking function assessment using optical motion capture and bi-plane dynamic X-ray imaging pre- and post-hemipelvectomy. |
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| Retrospective Group | No Intervention |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Functional Assessment | Other | Undergo walking function assessment with optical motion capture |
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| Measure | Description | Time Frame |
|---|---|---|
| To establish the patient-specific computational models to inform surgical decisions and design custom implants that maximize post-surgery function. | through study completion, an average of 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Valerae O Lewis, BS,MD | Contact | (713) 792-5073 | volewis@mdanderson.org |
| Name | Affiliation | Role |
|---|---|---|
| Valerae O Lewis | M.D. Anderson Cancer Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| M D Anderson Cancer Center | Recruiting | Houston | Texas | 77030 | United States |
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| Label | URL |
|---|---|
| M D Anderson Cancer Center | View source |
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| ID | Term |
|---|---|
| D014965 | X-Rays |
| ID | Term |
|---|---|
| D060733 | Electromagnetic Radiation |
| D055590 | Electromagnetic Phenomena |
| D060328 | Magnetic Phenomena |
| D055585 | Physical Phenomena |
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| X-Ray Imaging | Procedure | Undergo bi-plane dynamic X-ray imaging |
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| D011827 | Radiation |
| D011839 | Radiation, Ionizing |