Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Decreased pulmonary function, peripheral muscle strength, and exercise capacity were reported in primary ciliary dyskinesia (PCD) in recent studies. We aimed to investigate the data conducted between 10 July 2015 and 10 January 2015 of pulmonary function, respiratory muscle strength, exercise capacity, physical fitness, and activities of daily living (ADL) in PCD and healthy counterparts retrospectively at the first stage of the study and the effects of inspiratory muscle training on pulmonary function, respiratory muscle strength, and exercise capacity in PCD patients with decreased inspiratory muscle strength from the database recorded between 10 July 2015 and 10 January 2015 retrospectively at the second stage of the study.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Primary Ciliary Dyskinesia (PCD) | The first stage of the study: Data of 20 PCD patients from the database recorded between 10 July 2015 and 10 January 2017. The second stage of the study: -Data of 14 PCD patients who had lower inspiratory muscle strength from the same database underwent supervised inspiratory muscle training (IMT) with tapered flow resistive loading using Powerbreathe K5 device at our research unit and airway clearance techniques (ACT) as a home-based therapy for 6 weeks from the database recorded between 10 July 2015 and 10 January 2017. |
| |
| Healthy Group | Data of 20 healthy subjects from the database recorded between 10 July 2015 and 10 January 2017. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Data Collection | Other | The first stage of the study: Retrospective data collection of pulmonary function, respiratory muscle strength, exercise capacity, physical fitness, and activities of daily living (ADL). The second stage of the study -Retrospective data of pulmonary function, respiratory muscle function, functional capacity before and after supervised inspiratory muscle training with POWERbreathe K5 device using tapered flow resistive loading and airway clearance techniques performed for 6 weeks in PCD with decreased respiratory muscle strength. |
| Measure | Description | Time Frame |
|---|---|---|
| A primer outcome for the first stage of the study: Physical fitness | Munich Physical Fitness Test (MFT) was used to evaluate physical fitness. It is a test with six parameters including ball bounce, sandbag throwing, bending, vertical jumping, hanging and step test. | 10 July 2015-10 January 2015-retrospectively |
| A primer outcome for the second stage of the study: Functional capacity | Functional capacity was evaluated with six minute walk test (6MWT). | 10 July 2015-10 January 2015-retrospectively |
| Measure | Description | Time Frame |
|---|---|---|
| Demographic features | The age was recorded in years. | 10 July 2015-10 January 2015-retrospectively |
| Demographic features | Weight was recorded in kilograms. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Patient group: PCD patients consulted from Hacettepe University, Faculty of Medicine, Department of Pediatric Chest Diseases, Child Health and Diseases/, Ankara, Turkey to our unit for evaluation in terms of respiratory physiotherapy were included in our study.
Healthy group: Healthy counterparts from our database of the previous studies were included in our study.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Hazal Sonbahar Ulu, MSc | Hacettepe University | Principal Investigator |
| Deniz Inal Ince, Prof. Dr. | Hacettepe University | Study Chair |
| Deniz Inal Ince, Prof. Dr. | Hacettepe University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hacettepe University | Ankara | Turkey (Türkiye) |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Data Collection | Other | -Retrospective data collection of pulmonary function, respiratory muscle function, exercise capacity, physical fitness, and activities of daily living (ADL). |
|
| 10 July 2015-10 January 2015-retrospectively |
| Demographic features | The length was saved in meters. | 10 July 2015-10 January 2015-retrospectively |
| Demographic features | Body mass index was calculated by dividing the weight by the square of the height (kg/m^2) and recorded. | 10 July 2015-10 January 2015-retrospectively |
| Pulmonary Function | Pulmonary function (FEV1 (forced expiratory volume in one second), FVC (forced vital capacity), FEV1/FVC, FEF25-75 (%) (forced expiratory volume 25-75 %) and PEF (peak expiratory flow)) assessed with a portable spirometer (Spirobank MIR, Italy). | 10 July 2015-10 January 2015-retrospectively |
| Respiratory muscle functions | Respiratory muscle strength (maximal inspiratory pressure (MIP);maximal expiratory pressure (MEP), respectively) was measured with a portable, electronic mouth pressure monitor (Micro Medical MicroMPM, UK) and recorded. For second stage of the study; average inspiratory flow, inspiratory volume, and inspiratory work was evaluated based on the outcomes of the Breathe-Link software using POWERbreathe K5 device before and after IMT with tapered flow resistive loading and recorded. | 10 July 2015-10 January 2015-retrospectively |
| Exercise Capacity | Exercise capacity was assessed with the modified shuttle walk test. | 10 July 2015-10 January 2015-retrospectively |
| Activities of Daily Living | Glittre activities of daily living (ADL) test was used to evaluate daily life activity. | 10 July 2015-10 January 2015-retrospectively |
| ID | Term |
|---|---|
| D002925 | Ciliary Motility Disorders |
| D007619 | Kartagener Syndrome |
| ID | Term |
|---|---|
| D012140 | Respiratory Tract Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D000072661 | Ciliopathies |
| D000015 | Abnormalities, Multiple |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D030342 | Genetic Diseases, Inborn |
| D001987 | Bronchiectasis |
| D001982 | Bronchial Diseases |
| D015619 | Respiratory System Abnormalities |
| D003914 | Dextrocardia |
| D006330 | Heart Defects, Congenital |
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D006331 | Heart Diseases |
| D012857 | Situs Inversus |
Not provided
Not provided
| ID | Term |
|---|---|
| D003625 | Data Collection |
| ID | Term |
|---|---|
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
Not provided
Not provided