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The French Society of Rheumatology cannot rule on the value of intra-articular injections of PRP due to the lack of hindsight and insufficient data. In fact, the injection protocols are very heterogeneous in terms of preparation method, the presence or not of leukocytes, the number of centrifugations, the volume injected, the ultrasound guidance, which makes it difficult to analyze the literature. The investigator objective is therefore to evaluate the effectiveness of combined injections of PRP and hyaluronic acid.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PRP + HA | two injections of PRP (plasma rich in platelets ), in combination with HA (hyaluronic acid) | ||
| HA alone | HA (hyaluronic acid) |
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| Measure | Description | Time Frame |
|---|---|---|
| change of the visual analogue scale (VAS) from the "PRP + HA" group on the "HA alone" group | up to one year |
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Inclusion Criteria:
Exclusion Criteria:
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Patients benefiting, in the context of knee osteoarthritis, from viscosupplementation alone or from two injections of PRP, in combination with HA, at the Amiens University Hospital.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| LAURE LE MONNIER, MD | Contact | 03 22 66 82 50 | lemonnier.laure@chu-amiens.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Amiens | Recruiting | Amiens | 80480 | France |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| D012216 |
| Rheumatic Diseases |