Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Is post-bariatric body contouring surgery prevent weight regain or no, and what is the effect on the patient's Metabolism? Few literature studies report body contouring surgery to be positively associated with maintained weight loss after obesity surgery but the measures of outcomes are diverse, and the collective magnitude of such an association is unknown.
The changes in gastrointestinal hormones, adipokines, and cytokines as well as in hypothalamic neuropeptides and neurotransmitters resemble the changes observed in the anorexia/cachexia, suggesting that bariatric surgery triggers a catabolic state responsible for loss of appetite and prolonged body weight reduction.
Weight regain after gastric bypass surgery occurs in about half of all patients within 2 years. About 50% of patients eventually gain a little weight back after hitting their low point. We need a more thorough evaluation to determine what factors - medical, psychological, lifestyle - are involved in the weight gain. One of the factors that seem to be responsible for the degree and durability of weight loss is post-bariatric body contouring procedures. However, metabolic consequences of removing excess subcutaneous adipose tissue by body contouring procedures have to a lesser extent been explored
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group A | Experimental | to know the effect of post-bariatric body contouring surgery on weight loss and metabolism |
|
| group B | No Intervention | compare this group of patients with group A to detect weight changes and metabolic changes without any post-bariatric intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| body contouring | Procedure | any post-bariatric body contouring surgery included |
|
| Measure | Description | Time Frame |
|---|---|---|
| Weight Changes by Kilograms | to know the effect of post-bariatric body contouring surgery in weight. Detect the weight cahnges of the patient 3 and 6 months after body contouring surgery and body mass index also measured | 6 months |
| Level of Tumor Necrotizing Factor Alfa in Blood | Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. Tumor necrotizing factor alfa increase afer bariatric surgery and we want to know if its complete on increasing after body contouring surgeries or decresae . Tnf-a is measured by pg/ml | 6 months |
| Level of BNP in Blood | Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. BNP highly increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in the level of BNP. BNP unit is pg/ml | 6 months |
| Level of High Sensitive CRP in Blood | Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. hsCRP increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in blood level of hsCRp. The unit of hsCRP is mg/dl. | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Patient Satisfaction Score | From 1 to 5 . 1 very dissatisfied 5 very satisfied Increase in number means increase satisfaction. | 6 months |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Mohamed Shadad, Master | Assiut University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assiut University | Asyut | Asyut Governorate | 088 | Egypt |
It will be shared as numbers and the name of participants will not shared
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Title | Description |
|---|---|---|
| FG000 | Group A | to know the effect of post-bariatric body contouring surgery on weight loss and metabolism body contouring: any post-bariatric body contouring surgery included |
| FG001 | Group B | compare this group of patients with group A to detect weight changes and metabolic changes without any post-bariatric intervention |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
Not provided
Not provided
| ID | Title | Description |
|---|---|---|
| BG000 | Group A | to know the effect of post-bariatric body contouring surgery on weight loss and metabolism body contouring: any post-bariatric body contouring surgery included |
| BG001 | Group B |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Categorical | Count of Participants |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Weight Changes by Kilograms | to know the effect of post-bariatric body contouring surgery in weight. Detect the weight cahnges of the patient 3 and 6 months after body contouring surgery and body mass index also measured | Posted | Mean | Standard Deviation | Kilo gram | 6 months |
|
6 months
No risky intervention in follow up
Not provided
| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Group A | to know the effect of post-bariatric body contouring surgery on weight loss and metabolism body contouring: any post-bariatric body contouring surgery included |
Not provided
| Term | Organ System | Source Vocabulary | Assessment Type | Notes | Statistical Information |
|---|---|---|---|---|---|
| Echymosis | Skin and subcutaneous tissue disorders | Systematic Assessment |
Not provided
| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| MOHAMED Shadad rateb | AssiutU | 00201020575457 | m_shadad@aun.edu.eg |
Not provided
| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Mar 2, 2026 | Apr 11, 2026 | Prot_SAP_000.pdf |
Not provided
| ID | Term |
|---|---|
| D000073880 | Body Contouring |
| ID | Term |
|---|---|
| D003357 | Cosmetic Techniques |
| D013812 | Therapeutics |
| D019651 | Plastic Surgery Procedures |
| D013514 | Surgical Procedures, Operative |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
compare this group of patients with group A to detect weight changes and metabolic changes without any post-bariatric intervention
| BG002 | Total | Total of all reporting groups |
| Participants |
|
| Age, Continuous | Mean | Standard Deviation | years |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Race (NIH/OMB) | Count of Participants | Participants |
|
| Region of Enrollment | Number | participants |
|
| Units | Counts |
|---|---|
| Participants |
|
|
| Primary | Level of Tumor Necrotizing Factor Alfa in Blood | Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. Tumor necrotizing factor alfa increase afer bariatric surgery and we want to know if its complete on increasing after body contouring surgeries or decresae . Tnf-a is measured by pg/ml | Posted | Mean | Standard Deviation | Pico gram per ml | 6 months |
|
|
|
| Primary | Level of BNP in Blood | Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. BNP highly increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in the level of BNP. BNP unit is pg/ml | Posted | Mean | Standard Deviation | Pico gram per ml | 6 months |
|
|
|
| Primary | Level of High Sensitive CRP in Blood | Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. hsCRP increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in blood level of hsCRp. The unit of hsCRP is mg/dl. | Posted | Mean | Standard Deviation | Mg per dl | 6 months |
|
|
|
| Secondary | Patient Satisfaction Score | From 1 to 5 . 1 very dissatisfied 5 very satisfied Increase in number means increase satisfaction. | Posted | Mean | Full Range | Scores in scale | 6 months |
|
|
|
| 0 |
| 30 |
| 0 |
| 30 |
| 10 |
| 30 |
| EG001 | Group B | compare this group of patients with group A to detect weight changes and metabolic changes without any post-bariatric intervention | 0 | 30 | 0 | 30 | 12 | 30 |
Not provided
Not provided
Not provided
| 6 months after body contouring |
|
| 6 months after body contouring |
|
| 6 months after body contouring |
|