Remimazolam and Remifentanil Without Neuromuscular Blocki... | NCT05025410 | Trialant

Remimazolam and Remifentanil Without Neuromuscular Blocki... | NCT05025410 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
General anesthesia using remimazolam and remifentanil		Adult female patients scheduled for gynecological surgery under general anesthesia using remimazolam and remifentanil	Drug: Remimazolam

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Remimazolam	Drug	Loading for anesthesia induction: Remimazolam 6 mg/kg/h until loss of consciousness Continuous infusion for anesthesia maintenance: Remimazolam 1-2 mg/kg/h under the Bispectral index monitoring

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Remimazolam induction dose		During the anesthesia induction (from initiation of anesthesia until the insertion of laryngeal mask airway)
Remimazolam maintenance dose		During the anesthesia maintenance (from the insertion of laryngeal mask airway until stopping remimazolam infusion)

Secondary Outcomes

Measure	Description	Time Frame
Use of rescue midazolam		During the anesthesia (from initiation of anesthesia until stopping remimazolam infusion)
Use of rescue rocuronium		During the anesthesia (from initiation of anesthesia until stopping remimazolam infusion)

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
35883039	Derived	Park I, Cho M, Nam SW, Hwang JW, Do SH, Na HS. Total intravenous anesthesia induced and maintained by a combination of remimazolam and remifentanil without a neuromuscular blocking agent: a prospective, observational pilot study. BMC Anesthesiol. 2022 Jul 26;22(1):237. doi: 10.1186/s12871-022-01779-2.

Condition Browse Module