Desflurane and Sevoflurane Minimal Flow Anesthesia on Recovery and Anesthetic Depth

Comparison of Desflurane and Sevoflurane Minimal Flow Anesthesia on Recovery Parameters and Anesthetic Depth: a Randomized Prospective Study

Minimal flow anesthesia has economic and environmental advantages in addition to providing earlier recovery following general anesthesia. There is a paucity of data concerning the effect of minimal flow anesthesia (fresh gas flow <0,5 l/min) on recovery parameters. The primary objective of this study is to compare the recovery parameters of desflurane and sevoflurane in minimal flow anesthesia while the secondary objective is to compare the effect of these agents on anesthetic depth using bispectral index.

Inclusion Criteria:

• Ages between 18 and 65
• Patients undergoing elective surgery under general anesthesia
• Patients with an American Society of Anesthesiologists Classification I or II

Exclusion Criteria:

• Patient refusal
• Emergency surgery
• Patients with a contraindication for minimal flow anesthesia
• Uncontrolled diabetes mellitus
• History of serious systemic disease (cardiac, pulmonary, hepatic)
• Utilization of another analgesic technique such as central or peripheral nerve blocks