Perioperative Glutamine Supplementation and Cachexia | NCT05023499 | Trialant

Perioperative Glutamine Supplementation and Cachexia | NCT05023499 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
With glutamine supplementation		perioperative glutamine supplementation (PGS) was defined as the subjects with five-day parenteral plus one-month oral use.	Drug: SYMPT-X Glutamine, Oral Powder for Reconstitution
Without glutamine supplementation		no glutamine use	Drug: SYMPT-X Glutamine, Oral Powder for Reconstitution

Interventions

Name	Type	Description	Arm Group Labels	Other Names
SYMPT-X Glutamine, Oral Powder for Reconstitution	Drug	erioperative glutamine supplementation (PGS) was defined as the subjects with five-day parenteral plus one-month oral use.

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
area psoas major muscle (PMMA; cm2)	We hypothesized that glutamine might play a role in improving sarcopenia. Both the PMMA and total volume of the psoas major muscle (PMMV) represent the severity of sarcopenia, because CT is routinely performed in surgical GA patients to check for cancer recurrence. The reason of including total volume into analysis is that it is considered a better index to define sarcopenia. [21] The primary and secondary endpoints were the perioperative change of PMMA and PMMV, respectively.	3 month after surgery
volume of psoas major muscle (PMMV; cm3)	We hypothesized that glutamine might play a role in improving sarcopenia. Both the PMMA and total volume of the psoas major muscle (PMMV) represent the severity of sarcopenia, because CT is routinely performed in surgical GA patients to check for cancer recurrence. The reason of including total volume into analysis is that it is considered a better index to define sarcopenia. [21] The primary and secondary endpoints were the perioperative change of PMMA and PMMV, respectively.	3 month after surgery

Condition Browse Module