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Ridge split augmentation technique, with immediate implant placement, reduces the time of the treatment and the time of the final prosthetic reconstruction. Furthermore, compression of the bone increases its density. SMV is also found to promote osteogenic differentiation of bone marrow stem cells, suppress osteoclastic differentiation in bone tissue, and promotes osseointegration around implants in animal studies. The aim of this study is to compare surgical outcomes of the application of the alveolar ridge splitting (ARS) in combination with guided bone regeneration (GBR) using bone grafting and a barrier membrane, associated with immediate implant placement versus ARS in combination with the use of SMV with GBR using bone grafting and a barrier membrane, associated with immediate implant placement in patients with horizontally atrophic jaw bones.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ARS with GBR and SMV | Experimental | alveolar ridge splitting in combination with the use of GBR with SMV with immediate implant placement |
|
| alveolar ridge splitting with GBR | Active Comparator | alveolar ridge splitting in combination with the use of GBR without SMV with immediate implant placement |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Immediate implant placement and ARS with GBR and SMV | Procedure | Implant insertion and GBR for augmentation of the gap between buccal and lingual plate using bone graft mixed with SMV |
| Measure | Description | Time Frame |
|---|---|---|
| Measurements of the amount of bone formation in millimeters around immediately placed dental implants | Measurements of the amount of bone formation in millimeters using GBR with or without the combined effect of SMV in the ridge splitting following immediate implant placement. | 9 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Dalia R Issa, PhD | Kafrelsheikh University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry, Kafrelsheikh University | Kafr ash Shaykh | 33511 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38172458 | Derived | Issa DR, Elamrousy W, Gamal AY. Alveolar ridge splitting and simvastatin loaded xenograft for guided bone regeneration and simultaneous implant placement: randomized controlled clinical trial. Clin Oral Investig. 2024 Jan 4;28(1):71. doi: 10.1007/s00784-023-05427-y. |
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| Immediate implant placement and ARS with GBR | Procedure | Implant insertion and GBR for augmentation of the gap between buccal and lingual plate |
|
| ID | Term |
|---|---|
| C039746 | 4-azido-2-nitrophenyluridylyl pyrophosphate |
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