SVF Therapy for Human Knee Osteoarthritis

Evaluation of the Autologous Stromal Vascular Fraction Therapy for Knee Osteoarthritis

The purpose of the study is to asses the safety and efficacy of SVF for treatment of knee osteoarthritis, and establish a novel method to provide 3D MRI imaging for human knee cartilage to qualitatively and quantitatively evaluate cartilage regeneration.

Study participants voluntarily provided written informed consent to participate in the study. The two knees of each patient were randomly assigned to autologous SVF treatment group or non-treatment control group. The patients were evaluated every 4 weeks for safety and efficacy of autologous SVF therapy for 24 weeks.

Inclusion Criteria:

• Clinical diagnosis of Knee Osteoarthritis
• Articular cartilage defect grades I/II of both knee

Exclusion Criteria:

• autoimmune or inflammatory arthritis
• serious medical disorders