Andrographis extract, equivalent to andrographolide 20 mg per capsule, for a total of 180 mg of andrographolide per day, dosing into 3 capsules taking before meal for 3 times per day, for 5 days.

Boesenbergia extract, equivalent to pinostrobin 30 mg per capsule, for a total of 180 mg of pinostrobin per day, dosing into 2 capsules taking after meal for 3 times per day for 5 days.

Standard supportive treatment, as recommended by guideline from Ministry of Public Health, Thailand, there will be no antivirus given in this asymptomatic group

Andrographis extract, equivalent to andrographolide 20 mg per capsule, for a total of 180 mg of andrographolide per day, dosing into 3 capsules taking before meal for 3 times per day, for 5 days.

From WHO clinical progression scale (0-10):

0: Uninfected with no viral RNA detected

1. Asymptomatic with viral RNA detected
2. Symptomatic and independent
3. Symptomatic with assistance needed
4. Hospitalized with no oxygen therapy needed
5. Hospitalized with oxygen mask or nasal prongs
6. Hospitalized with oxygen by NIV or high flow
7. Intubation and mechanical ventilation with pO2/FiO2 >= 150 or SpO2/FiO2 >= 200
8. Mechanical ventilation with pO2/FiO2 < 150 (SpO2/FiO2 <200) or vasopressor
9. Mechanical ventilation with pO2/FiO2 < 150 and vasopressor, dialysis, or ECMO
10. Dead

Outcome 4 or more considered as hospitalization

From WHO clinical progression scale:

0: Uninfected with no viral RNA detected

1. Asymptomatic with viral RNA detected
2. Symptomatic and independent
3. Symptomatic with assistance needed
4. Hospitalized with no oxygen therapy needed
5. Hospitalized with oxygen mask or nasal prongs
6. Hospitalized with oxygen by NIV or high flow
7. Intubation and mechanical ventilation with pO2/FiO2 >= 150 or SpO2/FiO2 >= 200
8. Mechanical ventilation with pO2/FiO2 < 150 (SpO2/FiO2 <200) or vasopressor
9. Mechanical ventilation with pO2/FiO2 < 150 and vasopressor, dialysis, or ECMO
10. Dead

More on the scale - worse outcome