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| Name | Class |
|---|---|
| First Affiliated Hospital, Sun Yat-Sen University | OTHER |
| Third Affiliated Hospital, Sun Yat-Sen University | OTHER |
| Shantou Central Hospital | OTHER |
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To compare the perioperative, functional, and oncologic outcomes between non nerve sparing and nerve sparing robot-assisted radical cystectomy with orthotopic ileal neobladder in male patients with bladder cancer.
This study will enroll male patients with bladder cancer who will undergo robot-assisted radical cystectomy with orthotopic ileal neobladder. The patients will be distributed into two comparable groups according to surgical procedures: non nerve sparing group and nerve sparing group. Patient demographic and pathologic, perioperative, functional, and oncologic outcomes will be compared between the two groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| nerve sparing group | Patients will be preverved the neurovascular bundles during the resection of bladder and prostate of the operation. |
| |
| non nerve sparing group | Patients will receive standard radical cystectomy (not preserve the neurovascular bundles) during the operation. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| nerve sparing | Procedure | When resect the bladder and prostate, the neurovascular bundles around the prostate will be preserved. |
|
| Measure | Description | Time Frame |
|---|---|---|
| day-time continence rate | Patients were considered continent when they required 0 or 1 safety pad during the day-time. | 6 months |
| night-time continence rate | Patients were considered continent when they required 0 or 1 safety pad during the night. | 6 months |
| postoperative sexual function | The sexual function are evaluated by the International Index of Erectile Function-5 (IIEF-5). | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| perioperative complication rate | 3 months | |
| operative time | 24 hours | |
| estimated blood loss |
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Inclusion Criteria:
Exclusion Criteria:
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Enroll patients who received RARC.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kaiwen Li, MD | Contact | +86-15989252628 | likw6@mail.sysu.edu.cn | |
| Jian Huang, MD | Contact | +86-20-81332146 | huangj8@mail.sysu.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Jian Huang, MD | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sun Yat-sen Memorial Hospital, Sun Yat-sen University | Guangzhou | Guangdong | 510120 | China |
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| ID | Term |
|---|---|
| D001749 | Urinary Bladder Neoplasms |
| ID | Term |
|---|---|
| D014571 | Urologic Neoplasms |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| 24 hours |
| overall survival | 1 year |
| recurrence-free survival | 1 year |
| D052776 |
| Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D001745 | Urinary Bladder Diseases |
| D014570 | Urologic Diseases |
| D052801 | Male Urogenital Diseases |