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Acute kidney injury is one of the most common postoperative complications of acute type A aortic dissection, which is closely related to early postoperative death. Early prevention, early diagnosis and early treatment are the key to improve the prognosis of such patients. It has been a hot topic in clinical research for a long time. Previous reports revealed a series of risk factors for acute kidney injury after aortic dissection, but limited by research design and single modal data, high quality studies were rare. The purpose of this study is to further clarify the risk factors by studying the relationship between preoperative CT renal perfusion imaging indexes and postoperative acute kidney injury; establish and externally verify the multimodal radiomics prediction model for acute kidney injury after operation of aortic dissection combining with preoperative CT renal perfusion imaging and CT angiography information by analysis methods of information fusion, feature engineering and radiomics, so as to guide the follow-up clinical practice, improve the prognosis of such patients and save medical resources.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Normal Perfusion |
| ||
| Low Perfusion |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Normal CT Renal Perfusion imaging indexes | Diagnostic Test | A CT imaging which indicates the status of renal perfusion is normal. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Acute kidney injury after operation | Yes; No | From date of operation until the date of acute kidney injury or date of death from any cause, whichever came first, assessed up to 30 days. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients sufferred acute type A aortic dissection.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xin Zhao | Contact | +8618560086772 | zhaoxin3617@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Xin Zhao | Department of cardiac surgery, Qilu Hospital, Shandong University | Principal Investigator |
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| Low CT Renal Perfusion imaging indexes | Diagnostic Test | A CT imaging which indicates the status of renal perfusion is low. |
|
| ID | Term |
|---|---|
| D000784 | Aortic Dissection |
| D058186 | Acute Kidney Injury |
| ID | Term |
|---|---|
| D000094665 | Dissection, Blood Vessel |
| D000783 | Aneurysm |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D000094683 | Acute Aortic Syndrome |
| D001018 | Aortic Diseases |
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
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