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| Name | Class |
|---|---|
| University Ghent | OTHER |
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Until now, the use of invasive urodynamics with use of catheters is still the gold standard for lower urinary tract evaluation in subjects with CP. This suggests a psychological and physical impact of invasive urodynamics in subjects with CP and further demonstrates the need to avoid standard use of invasive urodynamics in children and adults with CP.
The current study will evaluate usefulness of uroflowmetry, correlation between uroflowmetry parameters and different lower urinary tract symptoms will be investigated. Secondly, results of uroflowmetry indicating possible vulnerability of the upper urinary tract will be defined.
A cross-sectional case-control study comparing children with CP and LUTS and children with CP without LUTS will be conducted with the primary objective to investigate correlation between uroflowmetry parameters and different LUTS.
Children will be evaluated with uroflowmetry and subsequent post void residual measurement and the validated vancouver symptom score for dysfunctional elimination syndrome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard toilet chair (hip angle 90°) | Experimental | uroflow measurement with subsequent post void residual measurement, conducted on a standard toilet chair. |
|
| Toilet chair with decreased hip angle | Experimental | uroflow measurement with subsequent post void residual measurement, conducted on a toilet chair with decreased hip angle. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| uroflow measurement | Device | Non-invasive urodynamic measurement wireless uroflowmeter UROCAP™ IV, Goby System Laborie |
|
| Measure | Description | Time Frame |
|---|---|---|
| Amount of pathological uroflow patterns - Qualitative assessment | Interpretation by pediatric urologist following ICCS classification Measured during uroflowmetry | During cross-sectional testing |
| Amount of pathological uroflow patterns - Quantitative assessment | Interpretation using Flow index methodology Measured during uroflowmetry | During cross-sectional testing |
| Maximal flow | Measured during uroflowmetry Qmax (mililitres/seconds | During cross-sectional testing |
| Measure | Description | Time Frame |
|---|---|---|
| Influencing factors for uroflow measurement |
| During cross-sectional testing |
| Voided volume |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Bieke Samijn, dr. | Ghent University Hospital/Ghent University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ghent University Hospital | Ghent | Flanders | 9000 | Belgium |
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| ID | Term |
|---|---|
| D002547 | Cerebral Palsy |
| D059411 | Lower Urinary Tract Symptoms |
| ID | Term |
|---|---|
| D001925 | Brain Damage, Chronic |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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Children will be randomised in two groups, with evaluation with a standard toilet seat or a toilet seat with decreased hip angle.
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|
| Bladder ultrasound | Device | Ultrasound of post void residual urine bladderscan CUBEscan BioCon 700 |
|
|
Measured during uroflowmetry mililitres Percentage of expected bladder capacity
| During cross-sectional testing |
| Post void residual urine | Measured with CUBEscan BioCon 700 mililiters Percentage of voided volume | During cross-sectional testing |
| D020924 | Urological Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |