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Percutaneous tibial nerve stimulation (PTNS) is an ambulatory therapy validated for patients with Faecal Incontinence (FI) refractory to conservative treatment with proved short and mid-term efficacy.
The investigators therefore aimed to evaluate the long-term efficacy of PTNS, considered 3 years of follow-up. The investigators also aimed to identify predictors of responses and suggest a new approach for partial responders.
Prospective single-centre cohort of patients with FI treated with PTNS was analysed.
PTNS sessions were performed in three phases: weekly for three months in the first phase, biweekly for three months in the second phase, and monthly for six months in the third and final phase.
Clinical control at the end of each phase and an additional follow-up was performed at 36 months. Wexner score, faecal urgency, bowel habits and quality of life for FI were assessed.
Patients were categorized in three groups: optimal responders when there was an improvement in Wexner score > 50%; partial responders if the improvement in Wexner score was 25-50%; and non-responders, when the improvement of Wexner score was < 25%.
Optimal responders and partial responders progressed into successive phases, whereas non-responders abandoned PTNS and other treatment options were offered.
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| Measure | Description | Time Frame |
|---|---|---|
| Change in faecal incontinence assessed by Wexner Score | Rate of patients with improvement in faecal incontinence assessed by Wexner score (Maximum punctuation: 20 being severe incontinence. Minimum punctuation: 0, no incontinence). | Baseline compared to 3, 6, 12 and 36 months after start of PTNS |
| Measure | Description | Time Frame |
|---|---|---|
| Predictors of good long-term improvement in Wexner score | Influence of previous obstetric or surgery history and duration of symptoms in the variation of Wexner score | At 3, 6 and 12 months after start of PTNS |
| Partial Responders |
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Inclusion Criteria:
Exclusion Criteria:
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Patients older than 18 years old, diagnosed with faecal incontinence (at least one or more episodes of faecal incontinence for more than 6 months) refractory to conservative treatment.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital General Universitario de Elche | Elche | Alicante | 03203 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15484348 | Background | Macmillan AK, Merrie AE, Marshall RJ, Parry BR. The prevalence of fecal incontinence in community-dwelling adults: a systematic review of the literature. Dis Colon Rectum. 2004 Aug;47(8):1341-9. doi: 10.1007/s10350-004-0593-0. | |
| 20416902 | Background | Maestre Y, Pares D, Vial M, Bohle B, Sala M, Grande L. [Prevalence of fecal incontinence and its relationship with bowel habit in patients attended in primary care]. Med Clin (Barc). 2010 Jun 12;135(2):59-62. doi: 10.1016/j.medcli.2010.01.031. Epub 2010 Apr 22. Spanish. |
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| ID | Term |
|---|---|
| D004688 | Encopresis |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001526 | Behavioral Symptoms |
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Incidence of patients with a decrease in Wexner score between 25 and 50% compared to initial value, and their performance in the long term
| At 3, 6 and12 months after start of PTNS |
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| 8561140 | Background | Johanson JF, Lafferty J. Epidemiology of fecal incontinence: the silent affliction. Am J Gastroenterol. 1996 Jan;91(1):33-6. |
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| 42332119 | Derived | Bosch-Ramirez M, Sanchez-Guillen L, Alcaide MJ, Serrano-Navidad M, Lopez-Rodriguez-Arias F, Sanchez-Romero A, Munoz-Duyos A, Arroyo A. Posterior tibial neurostimulation for faecal incontinence in community-dwelling older adults: long-term outcomes and predictors of response. Tech Coloproctol. 2026 Jun 22. doi: 10.1007/s10151-026-03379-5. Online ahead of print. |
| D001519 | Behavior |
| D019960 | Elimination Disorders |
| D001523 | Mental Disorders |