A Pilot Study in Endoscopic Therapy on Quality of Life and Pain in Chronic Pancreatitis

A Pilot Study in Endoscopic Therapy on Quality of Life and Pain in Chronic Pancreatitis: The EQuiPP Study

This study is a prospective study designed to assess the effect of pancreatic endotherapy on quality of life, pain levels, pancreatic exocrine function, and endocrine function.

Pancreatic endotherapy represents a potential treatment modality for patients with painful chronic pancreatitis. While pancreatic endotherapy is commonly performed, the effect of chronic pancreatitis on patient-centered outcomes remains poorly studied. Furthermore, the effect of endotherapy on pancreatic endocrine and exocrine are largely unknown. This study therefore aims to prospective observe patients with chronic pancreatitis after endotherapy is performed to better understand how it affects patient-centered outcomes such as pain and quality of life and pancreatic function. In doing so, the study also hopes to be able to predict which patients with chronic pancreatitis will benefit from pancreatic endotherapy.

Inclusion Criteria:

• Chronic Pancreatitis (as defined by the American Pancreatic Association Guidelines)
• Presence of Pain
• Referred for pancreatic endotherapy

Exclusion Criteria:

• Prior pancreatic endotherapy
• Prior pancreatic surgery
• Pregnant females
• Subjects unable to consent
• Imprisoned individuals