A New Way of Cardiac Denervation to Reduce the Incidence of AF After CABG.

Assessing a New Way of Cardiac Denervation to Reduce the Incidence of Atrial Fibrillation After Coronary Artery Bypass Grafting.

This is a prospective, random controlled trial(RCT) study. 430 patients undergoing coronary artery bypass grafting were enrolled. Our new way of cardiac denervation, defined as excision of Marshall ligament and Waterstone fat pad, was performed in 215 patients, and the other 215 patients were used as control subjects. All the patients need to equip with electronic monitor to record heart rhythms within 6 days after CABG. The investigators will compare the incidence of postoperative atrial fibrillation between two groups, and follow up 30 days after discharged.

Inclusion Criteria:

1. Patients undergoing simple CABG (on-pump/off-pump) for the first time.
2. Patients who signed the informed consent form and willing to undergo cardiac denervation.

Exclusion Criteria:

1. Age < 18；
2. Emergent CABG;
3. Cardiac surgery history；
4. Receiving other cardiac surgery except of CABG at the same time, such as Morrow、valvular surgery、ventricular aneurysm surgery、congenital heart diseases surgery；
5. Requiring mechanical or pharmacological therapy for hemodynamic support before CABG, such as ECMO or IABP;
6. History of AF ;
7. Taking antiarrhythmic agents except of beta-blockers last 2 weeks.