This study will investigate efficacy and safety of astaxanthin in 180 volunteers with refraction errors. Visual test, skin test, liver function test, renal function test, and adverse event will be evaluated before and after taking astaxanthin for 1 and 2 months.

This study will investigate efficacy and safety of astaxanthin in 180 volunteers with refraction errors. They will divided into 3 groups which are astaxanthin 4 mg group , astaxanthin 6 mg group, and placebo group. They will take the sample 1 capsule once daily for 2 months. Visual test, skin test, liver function test, renal function test, and adverse event will be evaluated before and after taking the sample for 1 and 2 months.

Inclusion Criteria:

• Age 18-65 years
• Refraction errors, dry eye, or blurred vision
• Have a willingness to participate in the study

Exclusion Criteria:

• Uncontrolled disease
• Have complications during the study
• Have astaxanthin more than 2 weeks
• Allergic to astaxanthin, seafood, or seaweed
• Osteoporosis or thyroid disease
• Immunodeficiency or taking immunosuppressants
• Liver and kidney diseases
• A person with a brain disorder, vision or hearing unusual
• Pregnancy or lactation
• Cannot follow the protocol
• During participated in other studies