Business/strategic reasons and low accrual rate

This is a prospective single arm, single center study estimating percentage of successful critical anatomy recognition in laparoscopic cholecystectomy surgeries using SPY fluorescence imaging and ICG, with each surgery also providing a white light 360 degree images.

The primary objective is to determine the percentage of successful critical anatomy recognition using intra-operative SPY fluorescence imaging and ICG: and to describe complications associated with intra-operative decision making in patients undergoing laparoscopic cholecystectomy.

Inclusion Criteria:

• Subject is 18 years of age or older
• Subject is scheduled to undergo laparoscopic cholecystectomy, elective or emergent
• Subject provides informed consent and signs an approved informed consent document for the study
• Subject is willing to comply with the protocol and study visit schedule

Exclusion Criteria:

• Subject is pregnant or lactating
• Subject has a known allergy or history of adverse reaction to ICG, iodine or iodine dyes
• Subject has known history of cholangitis, pancreatitis, prior bile duct injury, coagulopathy or known pre-existing liver disease
• Subjects who, in the Investigator's opinion, have any medical condition that may make the subject a poor candidate for the investigation, interferes with the interpretation of study results, or integrity of the study