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This is a single-arm longitudinal feasibility study for older adults that involves a 12-week home-based Tai Chi program and includes four remote and/or in-person data collection visits. The investigators will collect additional clinical data in a subset of participants who agree to undergo additional assessments in the Motion Analysis Laboratory at the Spaulding Rehabilitation Hospital in Boston, MA during two in-person data collection sessions. The investigators will assess feasibility and acceptability of the Tele-Tai Chi intervention; explore changes in clinically relevant outcome measures including: physical activity, self-efficacy, quality of life, balance, and gait; and evaluate longitudinal changes in Tai Chi proficiency.
The overall goal of the study is to test the delivery of a novel Tele-Tai Chi (TC) intervention in a single-arm feasibility study for community-dwelling TC-naïve older adults. The investigators will assess feasibility and acceptability of the Tele-TC intervention and its specific components through both qualitative and quantitative feedback, as well as the systematic tracking of adherence data to inform future trials and potential clinical use of the Tele-TC system. The investigators will also explore changes in outcome measures including physical activity, self-efficacy, quality of life, and gait, and evaluate changes in TC proficiency.
Over the course of the 12-week program, participants will be assessed 4 times (baseline, two follow-up assessments at 4 and 8 weeks respectively, and a final assessment at 12 weeks).
Study volunteers will be instructed to train on their own at least three times a week and to participate in 1:1 live sessions with TC instructors two or more times during the study period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tele-Tai Chi | Experimental | Tele-Tai Chi intervention |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tele-Tai Chi | Device | 12-week simplified TC program using the Tele-TC platform at home, with recommended training sessions at least three times a week, and two or more supplementary live sessions. |
| Measure | Description | Time Frame |
|---|---|---|
| Protocol Adherence | The percentage of Tai Chi home practice sessions completed by participants. | Post-intervention (approximately 12 weeks) |
| Retention | The percentage of participants who complete the study. | Through study completion, approximately 12 weeks from the beginning of the study |
| System Usability Scale | The scale is based on a 10-item questionnaire with five response options (from Strongly agree to Strongly disagree) in which participants rate the usability of the system. The scale ranges from 0 to 100, with higher scores indicating greater usability. | Post-intervention (approximately 12 weeks) |
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| Measure | Description | Time Frame |
|---|---|---|
| Ease of Use of the Tele-Tai Chi Platform (Qualitative Interview) | Qualitative interview about ease of use of the Tele-Tai Chi platform. The outcome will be the percentage of participants who provide positive feedback regarding the platform's ease of use. | Post-intervention (approximately 12 weeks) |
| Changes From Baseline in Activities-specific Balance Confidence (ABC) Scores |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Paolo Bonato, PhD | Spaulding Rehabilitation Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Spaulding Rehabilitation Hospital | Boston | Massachusetts | 02129 | United States |
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| ID | Title | Description |
|---|---|---|
| FG000 | Tele-Tai Chi | Tele-Tai Chi intervention Tele-Tai Chi: 12-week simplified TC program using the Tele-TC platform at home, with recommended training sessions at least three times a week, and two or more supplementary live sessions. |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
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| ID | Title | Description |
|---|---|---|
| BG000 | Tele-Tai Chi | Tele-Tai Chi intervention Tele-Tai Chi: 12-week simplified TC program using the Tele-TC platform at home, with recommended training sessions at least three times a week, and two or more supplementary live sessions. |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Categorical | Count of Participants |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Protocol Adherence | The percentage of Tai Chi home practice sessions completed by participants. | All dataset was considered | Posted | Mean | Standard Deviation | percentage of session completed | Post-intervention (approximately 12 weeks) |
|
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12 weeks
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Tele-Tai Chi | Tele-Tai Chi intervention Tele-Tai Chi: 12-week simplified TC program using the Tele-TC platform at home, with recommended training sessions at least three times a week, and two or more supplementary live sessions. |
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| Term | Organ System | Source Vocabulary | Assessment Type | Notes | Statistical Information |
|---|---|---|---|---|---|
| Back Pain | Musculoskeletal and connective tissue disorders | SNOMED CT | Non-systematic Assessment | Reports of back pain, including low back pain. Most cases were pre-existing with flares occurring during the study. Others reported non-study related activities as the cause. No relation to intervention, all cases mild. |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Paolo Bonato, PhD | Spaulding Rehabilitation Hospital | 617-952-6319 | pbonato@mgh.harvard.edu |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Aug 6, 2021 | Oct 14, 2024 | Prot_SAP_000.pdf |
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Activities-specific Balance Confidence (ABC): 16-item self-report measure in which participants rate their balance confidence to perform motor activities. The minimum score is 0. The maximum score is 100. Positive changes (i.e., higher scores post-intervention) would represent a positive outcome. |
| Baseline and post-intervention (approximately 12 weeks) |
| Changes From Baseline in Patient-Reported Outcomes Measurement Information System (PROMIS) 29 Scores | The PROMIS 29 instrument is a 29-item questionnaire assessing each of the following domains: anxiety, depression, fatigue, physical function, pain interference, pain intensity, sleep disturbance, and ability to participate in social roles and activities. The minimum score is 4 per domain, except for pain intensity for which the minimum score is 0. The maximum score per domain is 20, except for pain intensity for which the maximum score is 10. For the physical function and the ability to participate in social roles and activities domains a high score is indicative of positive outcome. For the anxiety, depression, fatigue, sleep disturbance, pain interference, and pain intensity a low score is indicative of positive outcome. | Baseline and post-intervention (approximately 12 weeks) |
| Changes From Baseline in Physical Activity Scale for the Elderly (PASE) | Physical Activity Scale for the Elderly (PASE): self-reported level of physical activity in individuals aged 65 years or older during the previous 7 days. The score accounts for the type of activities performed and the time of performance of each activity. The minimum score is 0. The scale has theoretical maximum value of 864, if subjects spent 24 hours per day over 7 days engaged in vigorous activities. However, as this is not possible, a maximum value of 400 is typically considered as that would correspond to being engage in vigorous activities for 8 hours per day + more moderate activities for 4.5 hours per day. | Baseline and post-intervention (approximately 12 weeks) |
| Changes From Baseline in Trail Making Test A/B Scores | Trail Making Test (TMT): Test to assess executive cognitive function. It has two parts: TMT A (number sequence only) considers visual search, and TMT B (alternating numbers and letters) evaluates executive control. The participant is asked to draw a line between 24 circles randomly arranged on a page that have to be linked in consecutive order. The TMT is scored by how long it takes to complete the test. | Baseline and post-intervention (approximately 12 weeks) |
| Changes From Baseline in Self-Efficacy Exercise (SEE) Questionnaire | Exercise Self-efficacy Questionnaire (SEE): 9-item questionnaire that focuses on the self-efficacy expectations for exercise for older adults. The minimum score is 0. The maximum score is 90. Positive changes (i.e., higher scores post-intervention) would represent a positive outcome. | Baseline and post-intervention (approximately 12 weeks) |
| Changes From Baseline in Tai Chi Proficiency Scores | Tai Chi experts will use video recordings to score proficiency using a developed instrument to score each of the six Tai Chi movements performed by participants. The minimum score is 6. The maximum score is 30 per Tai Chi exercise. Positive changes (i.e., higher scores post-intervention) would represent a positive outcome. The change in Tai Chi proficiency score ranges from -24 to +24. A change equal to 0 represents no change in proficiency. | Change from Baseline at Post-Intervention (approximately 12 weeks) |
| Changes From Baseline in Timed-Up-and-Go | Timed-Up-and-Go: Test to determine fall risk. The participant is asked to stand up from a chair, walk 3 meters, turns 180°, walk 3 meters back, and sits back down with back resting against the chair. | Baseline and post-intervention (approximately 12 weeks) |
| Changes From Baseline in Timed-Up-and-Go Dual Task | Dual task Timed-Up-and-Go test: The participant is asked to stand up from a chair, walk 3 meters, turns 180°, walk 3 meters back, and sits back down with back resting against the chair while counting backwards by three. | Baseline and post-intervention (approximately 12 weeks) |
| Changes From Baseline in Single Leg Stance | Balance on each leg (two trials): The participant is asked to stand on one leg for as long as they can up to a maximum of 30 seconds. | Baseline and post-intervention (approximately 12 weeks) |
| Changes From Baseline in Sit-to-Stand Performance | Sit-to-Stand Test: The participant is asked to stand up from a chair while keeping their arms crossed across their chest and repeat the task as many times as possible during a period of 30 seconds. A higher count of completed repetitions is considered indicative of improved performance. | Baseline and post-intervention (approximately 12 weeks) |
| Postural Sway and Balance on Both Legs With Feet Shoulder-width Apart | Balance on both legs with feet shoulder-width apart: The participant is asked to stand with feet shoulder-width apart for about 20 seconds. A sensor positioned at the waist is used to track the displacement of the center of mass during the 20 second data collection (for each task). The root mean square (RMS) value of the acceleration data collected using the sensor positioned at the waist is estimated in the antero-posterior (AP) and medio-lateral (ML) directions for the middle 15 seconds of each experiment. Data is gathered at baseline and post-intervention and derived for each condition for a total of 4 variables. | Baseline and post-intervention (approximately 12 weeks) |
| Postural Sway and Balance on Both Legs With Feet Close to Each Other | Balance on both legs with feet close to each other: The participant is asked to stand with feet as close as possible (without contact between the feet) for about 20 seconds. A sensor positioned at the waist is used to track the displacement of the center of mass during the 20 second data collection (for each task). The root mean square (RMS) value of the acceleration data collected using the sensor positioned at the waist is estimated in the antero-posterior (AP) and medio-lateral (ML) directions for the middle 15 seconds of each experiment. Data is gathered at baseline and post-intervention and derived for a total of 4 variables. | Baseline and post-intervention (approximately 12 weeks) |
| Normalized-to-height Stride Length | Study participants will undergo an instrumented gait evaluation. Stride length will be defined as the distance from ipsilateral foot contact to the next ipsilateral foot contact during gait. Normalized-to-height stride length will be derived by computing the stride length using the gait evaluation equipment and dividing such value by the height of the study participant. | Baseline and post-intervention (approximately 12 weeks) |
| Stride Time Variability | Study participants will undergo an instrumented gait evaluation. Stride time will be defined as the time interval between two consecutive foot contacts of the same limb. Stride time variability will be computed as the standard deviation of the stride time estimates derived using the gait evaluation equipment. | Baseline and post-intervention (approximately 12 weeks) |
| Changes From Baseline in Activity Level | Physical activity (e.g. number of steps per day) derived using a wrist-worn activity monitor. | Baseline and end of intervention (approximately 12 weeks) |
| Changes From Baseline in Mini-Balance Evaluation Systems Test (MiniBEST) | MiniBEST Test: Test to assess dynamic balance. It is a 14-item test scored using a three-level ordinal scale. This test will be performed only in individuals who are willing to be tested in the laboratory (as opposed to via a remote visit). The minimum score is 0. The maximum score is 28. Positive changes (i.e., higher scores post-intervention) would represent a positive outcome. | Baseline and end of intervention (approximately 12 weeks) |
| Participants |
|
| Age, Continuous | Mean | Full Range | years |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Ethnicity (NIH/OMB) | Count of Participants | Participants |
|
| Race (NIH/OMB) | Count of Participants | Participants |
|
| Region of Enrollment | Number | participants |
|
|
|
| Primary | Retention | The percentage of participants who complete the study. | Posted | Number | percentage of subject retained | Through study completion, approximately 12 weeks from the beginning of the study |
|
|
|
| Primary | System Usability Scale | The scale is based on a 10-item questionnaire with five response options (from Strongly agree to Strongly disagree) in which participants rate the usability of the system. The scale ranges from 0 to 100, with higher scores indicating greater usability. | The dataset was incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | score on a scale | Post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Ease of Use of the Tele-Tai Chi Platform (Qualitative Interview) | Qualitative interview about ease of use of the Tele-Tai Chi platform. The outcome will be the percentage of participants who provide positive feedback regarding the platform's ease of use. | All dataset analyzed. | Posted | Number | percentage of participants | Post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Activities-specific Balance Confidence (ABC) Scores | Activities-specific Balance Confidence (ABC): 16-item self-report measure in which participants rate their balance confidence to perform motor activities. The minimum score is 0. The maximum score is 100. Positive changes (i.e., higher scores post-intervention) would represent a positive outcome. | The dataset was incomplete and extreme outliers were eliminated. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | score on a scale | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Patient-Reported Outcomes Measurement Information System (PROMIS) 29 Scores | The PROMIS 29 instrument is a 29-item questionnaire assessing each of the following domains: anxiety, depression, fatigue, physical function, pain interference, pain intensity, sleep disturbance, and ability to participate in social roles and activities. The minimum score is 4 per domain, except for pain intensity for which the minimum score is 0. The maximum score per domain is 20, except for pain intensity for which the maximum score is 10. For the physical function and the ability to participate in social roles and activities domains a high score is indicative of positive outcome. For the anxiety, depression, fatigue, sleep disturbance, pain interference, and pain intensity a low score is indicative of positive outcome. | The dataset was incomplete. | Posted | Mean | Standard Deviation | score on a scale | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Physical Activity Scale for the Elderly (PASE) | Physical Activity Scale for the Elderly (PASE): self-reported level of physical activity in individuals aged 65 years or older during the previous 7 days. The score accounts for the type of activities performed and the time of performance of each activity. The minimum score is 0. The scale has theoretical maximum value of 864, if subjects spent 24 hours per day over 7 days engaged in vigorous activities. However, as this is not possible, a maximum value of 400 is typically considered as that would correspond to being engage in vigorous activities for 8 hours per day + more moderate activities for 4.5 hours per day. | The dataset was incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | score on a scale | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Trail Making Test A/B Scores | Trail Making Test (TMT): Test to assess executive cognitive function. It has two parts: TMT A (number sequence only) considers visual search, and TMT B (alternating numbers and letters) evaluates executive control. The participant is asked to draw a line between 24 circles randomly arranged on a page that have to be linked in consecutive order. The TMT is scored by how long it takes to complete the test. | The dataset was incomplete. Participants with missing data were excluded from the analysis. For the analysis of Part A only 24 patients were considered. | Posted | Mean | Standard Deviation | seconds | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Self-Efficacy Exercise (SEE) Questionnaire | Exercise Self-efficacy Questionnaire (SEE): 9-item questionnaire that focuses on the self-efficacy expectations for exercise for older adults. The minimum score is 0. The maximum score is 90. Positive changes (i.e., higher scores post-intervention) would represent a positive outcome. | The dataset was incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | score on a scale | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Tai Chi Proficiency Scores | Tai Chi experts will use video recordings to score proficiency using a developed instrument to score each of the six Tai Chi movements performed by participants. The minimum score is 6. The maximum score is 30 per Tai Chi exercise. Positive changes (i.e., higher scores post-intervention) would represent a positive outcome. The change in Tai Chi proficiency score ranges from -24 to +24. A change equal to 0 represents no change in proficiency. | The dataset was incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | score on a scale | Change from Baseline at Post-Intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Timed-Up-and-Go | Timed-Up-and-Go: Test to determine fall risk. The participant is asked to stand up from a chair, walk 3 meters, turns 180°, walk 3 meters back, and sits back down with back resting against the chair. | The dataset was incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | seconds | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Timed-Up-and-Go Dual Task | Dual task Timed-Up-and-Go test: The participant is asked to stand up from a chair, walk 3 meters, turns 180°, walk 3 meters back, and sits back down with back resting against the chair while counting backwards by three. | The dataset was incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | seconds | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Single Leg Stance | Balance on each leg (two trials): The participant is asked to stand on one leg for as long as they can up to a maximum of 30 seconds. | The dataset was incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | seconds | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Sit-to-Stand Performance | Sit-to-Stand Test: The participant is asked to stand up from a chair while keeping their arms crossed across their chest and repeat the task as many times as possible during a period of 30 seconds. A higher count of completed repetitions is considered indicative of improved performance. | The dataset is incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | score on a scale | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Postural Sway and Balance on Both Legs With Feet Shoulder-width Apart | Balance on both legs with feet shoulder-width apart: The participant is asked to stand with feet shoulder-width apart for about 20 seconds. A sensor positioned at the waist is used to track the displacement of the center of mass during the 20 second data collection (for each task). The root mean square (RMS) value of the acceleration data collected using the sensor positioned at the waist is estimated in the antero-posterior (AP) and medio-lateral (ML) directions for the middle 15 seconds of each experiment. Data is gathered at baseline and post-intervention and derived for each condition for a total of 4 variables. | The dataset was incomplete. Participants with missing data were excluded from the analysis. The root mean square (RMS) value of the acceleration in the antero-posterior (AP) and medio-lateral (ML) directions at the waist sensor was calculated for middle 15 seconds of each experiment. | Posted | Mean | Standard Deviation | millimeters per second squared | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Postural Sway and Balance on Both Legs With Feet Close to Each Other | Balance on both legs with feet close to each other: The participant is asked to stand with feet as close as possible (without contact between the feet) for about 20 seconds. A sensor positioned at the waist is used to track the displacement of the center of mass during the 20 second data collection (for each task). The root mean square (RMS) value of the acceleration data collected using the sensor positioned at the waist is estimated in the antero-posterior (AP) and medio-lateral (ML) directions for the middle 15 seconds of each experiment. Data is gathered at baseline and post-intervention and derived for a total of 4 variables. | Data analysis was limited only to subjects who completed in the intervention and completed both baseline and post-intervention assessments. The root mean square (RMS) value of the acceleration in the antero-posterior (AP) and medio-lateral (ML) directions at the waist sensor was calculated for middle 15 seconds of each experiment. | Posted | Mean | Standard Deviation | millimeters per second squared | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Normalized-to-height Stride Length | Study participants will undergo an instrumented gait evaluation. Stride length will be defined as the distance from ipsilateral foot contact to the next ipsilateral foot contact during gait. Normalized-to-height stride length will be derived by computing the stride length using the gait evaluation equipment and dividing such value by the height of the study participant. | The dataset is incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | unitless | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Stride Time Variability | Study participants will undergo an instrumented gait evaluation. Stride time will be defined as the time interval between two consecutive foot contacts of the same limb. Stride time variability will be computed as the standard deviation of the stride time estimates derived using the gait evaluation equipment. | The dataset was incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | milliseconds | Baseline and post-intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Activity Level | Physical activity (e.g. number of steps per day) derived using a wrist-worn activity monitor. | The dataset was incomplete. Participants with missing data were excluded from the analysis. | Posted | Mean | Standard Deviation | steps per day | Baseline and end of intervention (approximately 12 weeks) |
|
|
|
| Other Pre-specified | Changes From Baseline in Mini-Balance Evaluation Systems Test (MiniBEST) | MiniBEST Test: Test to assess dynamic balance. It is a 14-item test scored using a three-level ordinal scale. This test will be performed only in individuals who are willing to be tested in the laboratory (as opposed to via a remote visit). The minimum score is 0. The maximum score is 28. Positive changes (i.e., higher scores post-intervention) would represent a positive outcome. | Data analysis was limited only to subjects who completed both baseline and post-intervention assessments in the laboratory. | Posted | Mean | Standard Deviation | score on a scale | Baseline and end of intervention (approximately 12 weeks) |
|
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|
| 0 |
| 26 |
| 0 |
| 26 |
| 14 |
| 26 |
|
| Flu-like illness | Respiratory, thoracic and mediastinal disorders | SNOMED CT | Non-systematic Assessment | Reports of flu-like symptoms during study. All cases self-resolved with supportive care. |
|
| Fall | Injury, poisoning and procedural complications | SNOMED CT | Non-systematic Assessment | Reports of falls during non-study-related activities. No medical care required. |
|
| Headache | General disorders | SNOMED CT | Non-systematic Assessment | Reports of headache during non-study-related activities. |
|
| Knee Pain | Musculoskeletal and connective tissue disorders | SNOMED CT | Non-systematic Assessment | Reports of knee pain in participants with pre-existing knee pain. |
|
| Delayed Onset Muscle Soreness | Musculoskeletal and connective tissue disorders | SNOMED CT | Non-systematic Assessment | Reports of muscle soreness primarily related to non-study-related activities. |
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| Skin Irritation | Skin and subcutaneous tissue disorders | SNOMED CT | Non-systematic Assessment | Reports of skin irritation related to use of wearable devices. |
|
| Dizziness | General disorders | SNOMED CT | Non-systematic Assessment | Reports of dizziness during non-study-related activities. |
|
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| Title | Measurements |
|---|---|
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| Fatigue |
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| Pain Interference |
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| Physical Function |
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| Sleep Disturbance |
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| Pain Intensity |
|
| Title | Measurements |
|---|---|
|
| ML-Post Intervention |
|
| Title | Measurements |
|---|---|
|
| ML - Post Intervention |
|