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This study will evaluate the effect of the subgingival application of Frankincense extract gel as an adjunct to scaling and root planning (SRP) in chronic periodontitis.
: twenty patients will be randomly selected and equally divided into Group I: will receive SRP only, group II: will receive SRP and Frankincense extract the gel. Subgingival application of Frankincense extract gel will be performed following initial SRP )day 1) and at 7, and 14 days. Clinical measurements included pocket depth (PD), bleeding on probing (BOP), and clinical attachment level (CAL). Real-time PCR was carried out to determine the effect of the treatment on Porphyromonas gingivalis (Pg). Clinical measurements and Plaque samples for PCR were recorded at baseline (before treatment), one, and three months after treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo group | Placebo Comparator | ten patients with sites suffering from mild chronic periodontitis sites will be treated with scaling and root planing (SRP) only |
|
| test group | Active Comparator | Ten patients with sites suffering from mild chronic periodontitis. sites will be treated with scaling and root planing (SRP) and subgingival application of Frankincense extract gel |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| scaling and root planing | Procedure | will receive scaling and root planing only |
|
| Measure | Description | Time Frame |
|---|---|---|
| probing pocket depth | probing pocket depth will be recorded at baseline, at site that will be treated | baseline |
| probing pocket depth | probing pocket depth will be recorded at 1 month at the site to be treated | 1 month |
| probing pocket depth | probing pocket depth will be recorded at 3 month at the site to be treated | 3 month |
| clinical attachment level | clinical attachment level will be recorded at baseline, | baseline |
| clinical attachment level | clinical attachment level will be recorded at , 1 month at the site to be treated | 1 month |
| clinical attachment level | clinical attachment level will be recorded at 3 months at the site to be treated | 3 month |
| bleeding on probing | bleeding on probingwill be recorded at baseline, at the site to be treated | baseline |
| bleeding on probing | bleeding on probingwill be recorded at 1, month at the site to be treated | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Doaa Ahmed yousef bayoumi | Tanta | Gharbia Governorate | 31511 | Egypt |
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| ID | Term |
|---|---|
| D055113 | Chronic Periodontitis |
| ID | Term |
|---|---|
| D010518 | Periodontitis |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D014080 | Tooth Exfoliation |
| D016745 | Root Planing |
| ID | Term |
|---|---|
| D009063 | Dental Physiological Phenomena |
| D055688 | Digestive System and Oral Physiological Phenomena |
| D012534 | Dental Scaling |
| D003777 | Dental Prophylaxis |
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twenty patients will be randomly be selected and equally divided into Group I: will receive SRP only, group II: will receive SRP and Frankincense extract the gel. Subgingival application of Frankincense extract gel will be performed following initial SRP )day 1) and at 7, and 14 days.
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| Frankincense extract gel natural herbal product | Procedure | will receive Scaling and root planing then. Subgingival application of Frankincense extract gel |
|
|
| bleeding on probing | bleeding on probingwill be recorded at 3 months at the site to be treated | 3 month |
| PCR for Porphyromonas gingivalis count | PCR for Porphyromonas gingivalis count be recorded at baseline, at the site to be treated | baseline |
| PCR for Porphyromonas gingivalis count | PCR for Porphyromonas gingivalis count be recorded at 1, and month at the site to be treated | 1 month |
| PCR for Porphyromonas gingivalis count | PCR for Porphyromonas gingivalis count be recorded at 3 months at the site to be treated | 3 month |
| D002908 |
| Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010517 | Periodontics |
| D003813 | Dentistry |
| D013357 | Subgingival Curettage |
| D011313 | Preventive Dentistry |