Lung Volume Perception and Impact of a Cognitive Task on Ventilation in Hypermobile Ehlers-Danlos Syndrome.

Lung Volume Perception and Impact of a Cognitive Task on Ventilation in Healthy Subjects and Subjects With Hypermobile Ehlers-Danlos Syndrome.

Patients with hypermobile Ehlers-Danlos syndrome have respiratory and proprioceptive disorders. The aim of this study is to explore whether there is an alteration in lung volume perception in patients with hEDS compared to healthy subjects, and whether a cognitive task can influence ventilation control differently in subjects with hEDS than in healthy subjects.

Inclusion Criteria (common):

• More than 18 years old
• Understanding French

Inclusion Criteria (hEDS Patients):

• hEDS diagnosis

Inclusion Criteria (healthy subjects):

• Age (±5 years), Gender and BMI (±2.5kg/m²) matching

Exclusion Criteria (common):

• Pregnancy

Exclusion Criteria (hEDS Patients):

• Respiratory comorbidity independent of hEDS
• Previous participation in a rehabilitation programme at the clinic

Exclusion Criteria (healthy subjects):

• Known respiratory or proprioceptive pathology
• Hypermobility (evaluated with the Beighton score)