Infections with enterobacteria producing carbapenemases at the University Hospitals of Strasbourg - descriptive epidemiology and risk factors for infection in the event of colonization

There is a worrying situation of an increase in the number of patients colonized with carbapenemase-producing Enterobacteriaceae (CPE) at HUS.

7 to 15% of patients colonized with EPC would develop an infection with EPC. The cohorts published mainly concern patients hospitalized in intensive care. The associated mortality reported in the literature is high (> 25%) and greater than that associated with infection with the same bacterium sensitive to carbapenems.

Inclusion criteria:

• Major subject (≥18 years old)
• Subject hospitalized at HUS between 01/01/2011 and 07/31/2021
• Clinical sample or rectal screening smear finding an enterobacterium producing a carbapenemase (EPC)
• Subject not having expressed their opposition to participating in the study

Exclusion criteria:

• Subject having expressed opposition to participating in the study
• Subject under guardianship or guardianship
• Subject under safeguard of justice

Major subject with clinical sample or rectal screening smear finding an enterobacterium producing a carbapenemase