Non-invasive Measurement of Gastric Motility

Body Surface Gastric Mapping to Evaluate Patients With Upper Gastrointestinal Symptoms and Controls

Clinical evaluation to compare performance of the physiological recordings from the Gastric Alimetry System vs a predicate reference device (Medtronic Polygram NET / Polygraf ID EGG System

A prospective, non-randomised, single centre investigation on patients with suspected motility disorders comprising a simultaneous head-to-head comparison of device performance between the Gastric Alimetry System and the Medtronic Polygram NET / Polygraf ID EGG System.

Inclusion Criteria:

• Age 22 years old or older
• Able to provide written informed consent
• Patients with a suspected motility disorder, meetingRome IVCriteria for functional dyspepsia or chronic nausea and vomiting syndromes or having a diagnosis of gastroparesis as confirmed by a standardized gastric scintigraphy study, including having >10% gastric meal retention at 4-hours.

Exclusion Criteria:

• BMI >35 kg m(2)
• Known metabolic, neurogenic or endocrine disorders known to cause gastrointestinal dysmotility e.g. multiple sclerosis, Parkinson's disease, hypothyroidism
• Known current gastrointestinal infection (includes H.pylori when being actively treated)
• Known current inflammatory bowel disease
• Known current gastrointestinal malignancy
• Previous gastroduodenal surgery
• Open abdominal wounds or abdominal skin not intact (e.g.rash, abrasions, weeping tissues)
• Fragile skin evidenced by high susceptibility to skin tears or skin that bruises easily
• Regular cannabis use
• Allergy to adhesives
• Pregnancy