Not provided
Not provided
Not provided
Not provided
Not provided
Due to HEC supply issues at participating centers and low enrollment rate among eligible patients
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Pusan National University Yangsan Hospital | OTHER |
| Chungnam National University Sejong Hospital | OTHER |
Not provided
Not provided
Not provided
Comparison of clinical and radiological outcomes between bare platinum coil group and second-generation hydrogel coils for treatment of ruptured intracranial aneurysms.
The investigators aimed to analyze whether the use of second-generation hydrogel coils for the treatment of ruptured intracranial aneurysms improves clinical and angiographic outcomes compared with the use of bare platinum coils.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Second-generation hydrogel coil group | Experimental | Treatment using second-generation hydrogel coils (had to constitute > 50% of the total coil length) for ruptured cerebral aneurysms |
|
| Bare platinum coil group | Active Comparator | Treatment using bare metal coil only for ruptured cerebral aneurysms |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Coil embolization | Device | coil embolization for ruptured intracranial aneurysm with bare platinum coils or second-generation hydrogel coils |
|
| Measure | Description | Time Frame |
|---|---|---|
| any recurrence rate after treatment | any recurrence rate at 12 months after coil embolization | during 12 months after coil embolization |
| Measure | Description | Time Frame |
|---|---|---|
| rate of retreatment during 12 months follow-up period | rate of retreatment during 12 months follow-up period | rate of retreatment during 12 months follow-up period |
| packing density (%) after coil embolization |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| O-Ki Kwon | Seoul National University Bundang Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chungnam National University Sejong Hospital | Sejong | Chungcheongnam-do | 30099 | South Korea | ||
| Pusan National University Yangsan Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41844924 | Derived | Ban SP, Kwon OK, Kim YD, Shim HS, Sung SB, Kim CH, Byoun HS. Comparison of second-generation hydrogel embolic coils and bare platinum coils in ruptured intracranial aneurysm treatment: A prospective, multicenter, randomized controlled study. Neurosurg Rev. 2026 Mar 18;49(1):289. doi: 10.1007/s10143-026-04212-1. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D017542 | Aneurysm, Ruptured |
| D002532 | Intracranial Aneurysm |
| D000783 | Aneurysm |
| D012421 | Rupture |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D020765 | Intracranial Arterial Diseases |
| D002561 | Cerebrovascular Disorders |
Not provided
Not provided
bare platinum coils group versus second-generation hydrogel coil group
Not provided
Not provided
Not provided
Not provided
packing density (%) after coil embolization
| packing density (%) after coil embolization |
| Procedural complication | Procedural complication | during coil embolization |
| delayed cerebral ischemia during 12-month follow-up period | delayed cerebral ischemia during 12-month follow-up period | delayed cerebral ischemia during 12-month follow-up period |
| good clinical outcome (mRS score ≤ 2) at 12-month follow-up period | good clinical outcome (mRS score ≤ 2) at 12-month follow-up period | good clinical outcome (mRS score ≤ 2) at 12-month follow-up period |
| rate of ventriculoperitoneal shunt during 12-month follow-up period | rate of ventriculoperitoneal shunt during 12-month follow-up period | rate of ventriculoperitoneal shunt during 12-month follow-up period |
| coil's ease of manipulation | coil's ease of manipulation | during coil embolization |
| Yangsan |
| Gyeongsangnam-do |
| 50612 |
| South Korea |
| Seoul National University Bundang Hospital | Seongnam-si | 13620 | South Korea |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014947 | Wounds and Injuries |