To clarify the value of genomic testing in the clinical diagnosis or prognosis of pancreatic space occupation, provide a basis for the selection of clinical diagnosis methods for pancreatic space occupation, optimize clinical management strategies, and improve the prognosis of patients.

Inclusion Criteria:

1. Age 18-85, no gender limit
2. Imaging examinations suggest that the clear pancreas has clear space-occupying lesions
3. Admitted to our department, ready to undergo endoscopic ultrasound biopsy to confirm the diagnosis

Exclusion Criteria:

1. There are contraindications for endoscopic ultrasound biopsy
2. Failed to join the group or refused follow-up due to various reasons

Occupying lesions of the pancreas, specifically including benign diseases and malignant diseases, mainly pancreatic cancer has a very high incidence. Elderly patients, especially those who drink alcohol all year round, have a lot of occurrences, and many patients are already in the middle or advanced stage when they are diagnosed.